DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AsnRS-m and si:ch211-256m1.8

DIOPT Version :9

Sequence 1:	NP_611176.1	Gene:	AsnRS-m / 36909	FlyBaseID:	FBgn0034177	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	XP_001335682.4	Gene:	si:ch211-256m1.8 / 795494	ZFINID:	ZDB-GENE-131127-417	Length:	1574	Species:	Danio rerio

Alignment Length:	477	Identity:	113/477 - (23%)
Similarity:	195/477 - (40%)	Gaps:	114/477 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 VVVPRTPENQHLAP------GSVIAAVGKIQVAPNGSFELHANQVEMLAEG--RLQEGY------ 108
            |:|||.|....:..      ..:|.||.|:         .|..|..|.|.|  .:.||:
Zfish  1123 VLVPRKPHTSDIFRMNKSDYTDLIVAVRKV---------AHLLQDAMNARGVAIIFEGFEIDYAH 1178

  Fly   109 ----PFSPKQKHP------PEYVREHLHLRSRVDFVAAQ----MRVRHKAQKAI--HDYMDD--- 154
                |..|:...|      |::...:....:.||...|.    ..:..|..|.|  ..:.|.
Zfish  1179 AKLIPLVPQTNAPKPPAVAPQFCPTYKGYVTSVDGPPANEEDLSEIHSKITKTIPPQSWQDPLTH 1243

  Fly   155 ----------QDFVQINTPLLTT------NDCEGAGEVFRVQPDSQDLLKQMNRPNIPMEQSYFD 203
                      ::..||...|..:      |.|:..   :.:.|.:.|.:..      ||......
Zfish  1244 ASSAINSKWYRNLFQIQNTLFHSTVEYFNNKCKYG---YALTPITTDTISS------PMGLGSDS 1299

  Fly   204 SKVFLSVSGQ-LHL-EAMTY----------GLGKTYTLSPAFRAENSKSPLHLAEFYMFEAELAH 256
            ..||:::.|| ::| ::|.:          ||...|.:||:||.|:..: .||.:||..|.||
Zfish  1300 EPVFVNMLGQDVYLADSMQFVLEYFLRFHDGLPGAYYVSPSFRGEDPDA-THLNQFYHVECEL-- 1361

  Fly   257 LEEME--------KLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWKIMSYDE 313
            |.:|:        .:|...:.|||..::.:|.|:|       :.|::...|..|:.|...::.|:
Zfish  1362 LGDMDVAMSIAEGYVAHLTKAMLKQHSDIILNTAG-------KLSHAQELLKNLEGPLPRVALDQ 1419

  Fly   314 ALQVLQENKDSLKTPISLNEG-------FSKDQELFLVAHCGAPVFVVDWPAQQKPFYMK-VSRS 370
            |:.:: .:.|.|:.   :.||       .::..|..|:...|..|::.:......|||.. :..|
Zfish  1420 AIHIM-PSSDCLEW---VQEGQPQFGRKLTRKGEKVLIEKYGGAVWLTEMDHLGVPFYQAYIEDS 1480

  Fly   371 NPNRVHALDLLMPAVGELCGGSLRESDPAILK---SHPHLPKD-LEWYVDLRKYGGVPTGGFGMG 431
            ..::..|.|||: .:||..|...|.|.|.:::   .|..:|:| .:||:::|:...:.|.|:|||
Zfish  1481 GQSKAKAADLLL-GLGETVGLGERHSTPDMVREALQHHAVPEDSYKWYINMRQVMPLLTSGWGMG 1544

  Fly   432 FERYLQLVTGVKNIRDVIPFPR 453
            .||||..:....::||:...||
Zfish  1545 TERYLCWLLQHNDVRDMQIIPR 1566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS-m	NP_611176.1	asnC	13..460	CDD:235176	113/477 (24%)
		EcAsnRS_like_N	27..101	CDD:239813	12/48 (25%)
		AsxRS_core	115..456	CDD:238399	95/402 (24%)
si:ch211-256m1.8	XP_001335682.4	Carn_acyltransf	3..513	CDD:279140
		Asparaginase_2	636..916	CDD:271337
		PRK10226	639..912	CDD:182319
		Hit	1088..1232	CDD:223611	25/117 (21%)
		PRK06462	1233..1566	CDD:235808	85/356 (24%)
		class_II_aaRS-like_core	1256..1566	CDD:294192	84/333 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910