DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AsnRS-m and SLC25A37

DIOPT Version :9

Sequence 1:	NP_611176.1	Gene:	AsnRS-m / 36909	FlyBaseID:	FBgn0034177	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_057696.2	Gene:	SLC25A37 / 51312	HGNCID:	29786	Length:	338	Species:	Homo sapiens

Alignment Length:	223	Identity:	39/223 - (17%)
Similarity:	64/223 - (28%)	Gaps:	103/223 - (46%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RFYSKSGRIAQILKTN---KP--GDSLAIQG----------WIKNVRRLKNNTFLDINDGSTSSR 55
            ::.|..|.:.:|::|.   :|  |.::.|.|          ..:|::|..|:.|
Human    83 QYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVF----------- 136

  Fly    56 FQVVVPRTPENQHLAPGSVIAAVGKIQVAPNGSFELHANQVEMLAEGRLQEGYPFSPKQKHPPEY 120
                  ....|.|||.|  ||          ||.....:...|                 :|.|.
Human   137 ------HHQGNSHLANG--IA----------GSMATLLHDAVM-----------------NPAEV 166

  Fly   121 VREHLHL-----RSRVDFVAAQMRVRHKAQKAIHDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQ 180
            |::.|.:     ||.:..:....|.                              ||.|..:|..
Human   167 VKQRLQMYNSQHRSAISCIRTVWRT------------------------------EGLGAFYRSY 201

  Fly   181 PDSQDLLKQMNRPNIPMEQSYFDSKVFL 208
            .....:       |||.:..:|.:..||
Human   202 TTQLTM-------NIPFQSIHFITYEFL 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS-m	NP_611176.1	asnC	13..460	CDD:235176	37/216 (17%)
		EcAsnRS_like_N	27..101	CDD:239813	16/83 (19%)
		AsxRS_core	115..456	CDD:238399	17/99 (17%)
SLC25A37	NP_057696.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		Solcar 1	43..131		9/47 (19%)
		Mito_carr	44..136	CDD:278578	11/52 (21%)
		Solcar 2	141..225		27/148 (18%)
		Mito_carr	142..224	CDD:278578	26/147 (18%)
		Solcar 3	232..326
		Mito_carr	<252..330	CDD:278578
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1056670at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010