DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AsnRS-m and slc25a37

DIOPT Version :9

Sequence 1:	NP_611176.1	Gene:	AsnRS-m / 36909	FlyBaseID:	FBgn0034177	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001035060.1	Gene:	slc25a37 / 387000	ZFINID:	ZDB-GENE-031118-202	Length:	332	Species:	Danio rerio

Alignment Length:	336	Identity:	68/336 - (20%)
Similarity:	111/336 - (33%)	Gaps:	96/336 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 RVDFVAAQMRVRHKAQKAIHDYMDDQDFVQINTPL-----LTTNDCEGAGEVFRVQP-DSQDLLK 188
            |.|.|.|.:.:....:       :|:|:..:....     :|.....|..|...:.| ||.....
Zfish     4 RTDAVLASLEMSEPVK-------NDEDYESLPAHASLGTHMTAGAVAGILEHTVMYPVDSVKTRM 61

  Fly   189 QMNRPNIPMEQSYFDSKVFLSVSGQLHLEAMTYGL-----GKTYTLSPAFRAENSKSPLHLAEFY 248
            |..:|: |..|       :.||.|.|.....|.||     |...|:..|       .|.|...|.
Zfish    62 QSLQPD-PKAQ-------YRSVYGALKRIVRTEGLLRPLRGLNITVLGA-------GPAHALYFA 111

  Fly   249 MFEAELAHLEEM------EKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWK 307
            .:|.....|.::      ..:|..:...:.:|.:..:....|.:.  ||....||       |::
Zfish   112 CYERIKRSLSDVIQNGGNSHIANGVAGSVATVLHDAVMNPAEVVK--QRMQMYNS-------PYR 167

  Fly   308 IMSYDEALQVLQENKDSL-------KTPISLNEGFSKDQELFLVAHCGAPVFVVDWPAQQKPFYM 365
            .: ||..|.|  ..|:.|       .|.:::|..|.             .|..:.:...|:.|
Zfish   168 SL-YDCVLMV--SRKEGLAAFYRSYSTQLTMNIPFQ-------------AVHFITYEFMQEHF-- 214

  Fly   366 KVSRSNPNRVH-------------ALDLLMPAVGELCGGSLRESDPAILKSHPHLPKDLEWYVD- 416
                 ||:|.:             |:...:....::|...|...:...|.| .|:...|...|:
Zfish   215 -----NPHRQYRPETHIISGAAAGAVSAAVTTPLDVCKTLLNTQENVALSS-AHVSGHLSGMVNA 273

  Fly   417 LR---KYGGVP 424
            ||   :.||||
Zfish   274 LRTVYRLGGVP 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS-m	NP_611176.1	asnC	13..460	CDD:235176	68/336 (20%)
		EcAsnRS_like_N	27..101	CDD:239813
		AsxRS_core	115..456	CDD:238399	68/336 (20%)
slc25a37	NP_001035060.1	Mito_carr	30..122	CDD:278578	25/106 (24%)
		Solcar 1	31..119		24/102 (24%)
		PTZ00168	36..313	CDD:185494	62/297 (21%)
		Solcar 2	129..213		19/108 (18%)
		Mito_carr	130..218	CDD:278578	22/119 (18%)
		Solcar 3	220..314		14/66 (21%)
		Mito_carr	<240..318	CDD:278578	13/46 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1056670at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010