Protein Alignment AsnRS-m and DARS1

DIOPT Version :9

• Sequence 1: NP_611176.1
• Gene: AsnRS-m / 36909
• FlyBaseID: FBgn0034177
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001340.2
• Gene: DARS1 / 1615
• HGNCID: 2678
• Length: 501
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 113/419 - (26%)
• Similarity: 171/419 - (40%)
• Gaps: 91/419 - (21%)

  Fly    80 KIQVAPNGSFELHANQVEM--LAEGRLQEGYPFSPKQKHPPE---------YVREHLHLRSRV-D 132
            ||........|||..::.:  |||.||    |........||         .|.:...|.:|| |
Human   126 KIGSCTQQDVELHVQKIYVISLAEPRL----PLQLDDAVRPEAEGEEEGRATVNQDTRLDNRVID 186

  Fly   133 FVAAQMRVRHKAQKAI----HDYMDDQDFVQINTPLLTTNDCEGAGEVFRVQPDSQDLLKQMNRP 193
            ...:..:...:.|..|    .:.:.::.||:|.||.:.:...||...||.|
Human   187 LRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTV-------------- 237

  Fly   194 NIPMEQSYFDSKVFLSVSGQLHLE-AMTYGLGKTYTLSPAFRAENSKSPLHLAEFYMFEAELA-- 255
                  |||.:..:|:.|.||:.: .:.....|.:::.|.||||:|.:..||.||...:.|:|
Human   238 ------SYFKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFN 296

  Fly   256 -HLEE-MEKLAQFIEQMLKSVTNRLLETSGEDLSFCQRNSNSNSDLPWLQVPWKI------MSYD 312
             |..| ||::|..:.|:.|.:..|          |.......|...|.  .|:|.      :.|.
Human   297 YHYHEVMEEIADTMVQIFKGLQER----------FQTEIQTVNKQFPC--EPFKFLEPTLRLEYC 349

  Fly   313 EALQVLQE------NKDSLKTPISLNEGFSKDQELFLVAHC-----GAPVFVVD-WPAQQKPFYM 365
            |||.:|:|      ::|.|.||   ||.        |:.|.     ....:::| :|...:|||.
Human   350 EALAMLREAGVEMGDEDDLSTP---NEK--------LLGHLVKEKYDTDFYILDKYPLAVRPFYT 403

  Fly   366 KVSRSNPNRVHALDLLMPAVGELCGGSLRESDPAILKSHP-HLPKDLE---WYVDLRKYGGVPTG 426
            .....||.:.::.|:.|.. .|:..|:.|..||.:|.... |...|||   .|:|..::|..|..
Human   404 MPDPRNPKQSNSYDMFMRG-EEILSGAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPHA 467

  Fly   427 GFGMGFERYLQLVTGVKNIRDVIPFPRYP 455
            |.|:|.||...|..|:.|:|....|||.|
Human   468 GGGIGLERVTMLFLGLHNVRQTSMFPRDP 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS-m	NP_611176.1	asnC	13..460	CDD:235176	113/419 (27%)
		EcAsnRS_like_N	27..101	CDD:239813	6/22 (27%)
		AsxRS_core	115..456	CDD:238399	102/382 (27%)
DARS1	NP_001340.2	tRNA-synt_2	3..501	CDD:332564	113/419 (27%)
		Aspartate. /evidence=ECO:0000250	251..254		2/2 (100%)
		Binding site for the 3'-end of tRNA. /evidence=ECO:0000255	411..415		0/3 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0017
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810