DRSC/TRiP Functional Genomics Resources

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Protein Alignment ste24a and Oma1

DIOPT Version :9

Sequence 1:NP_611175.1 Gene:ste24a / 36908 FlyBaseID:FBgn0034176 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_080185.1 Gene:Oma1 / 67013 MGIID:1914263 Length:521 Species:Mus musculus


Alignment Length:178 Identity:42/178 - (23%)
Similarity:64/178 - (35%) Gaps:73/178 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   296 TDEEVLA-VLGHELGHWKLGHVTKNIIIMQVHLFLMFLVFGNVFKYPPFYVAMGFQPGTRPILVG 359
            ||...|: :||||:.|..|||..:...:  ||| |.||  |.:|                     
Mouse   312 TDVHQLSFLLGHEIAHAVLGHAAEKASL--VHL-LDFL--GMIF--------------------- 350

  Fly   360 LLIVFTYVLAPYNALMNFAMTILSRRFEY------------QADEFAFKLG-------------- 398
              :...:.:.|.::|......|.|:..||            :||:...:|.              
Mouse   351 --LTMIWAICPRDSLAVLGQWIQSKLQEYMFDRPYSRTLEAEADKVGLQLAAKACADVRASSVFW 413

  Fly   399 ----FAEQLGQALIKLNVDNLGFP-VYDWLYSTWNHSHPTLLQRLNRL 441
                |:|.|.           |:| :.:|| || :.||....:.|:||
Mouse   414 QQMEFSESLH-----------GYPKLPEWL-ST-HPSHGNRAEYLDRL 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ste24aNP_611175.1 Peptidase_M48_N 31..216 CDD:293100
HtpX 153..440 CDD:223575 40/175 (23%)
Peptidase_M48 219..439 CDD:279743 39/174 (22%)
Oma1NP_080185.1 Cardiolipin-binding. /evidence=ECO:0000269|PubMed:31819158 144..163
Stress-sensor region. /evidence=ECO:0000269|PubMed:24550258 161..191
M48C_Oma1_like 265..452 CDD:320690 42/178 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0501
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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