Protein Alignment ste24b and STE24

DIOPT Version :9

• Sequence 1: NP_611174.1
• Gene: ste24b / 36907
• FlyBaseID: FBgn0034175
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_012651.1
• Gene: STE24 / 853581
• SGDID: S000003878
• Length: 453
• Species: Saccharomyces cerevisiae
• Alignment Length: 472
• Identity: 135/472 - (28%)
• Similarity: 212/472 - (44%)
• Gaps: 87/472 - (18%)

  Fly    15 IIIAFLVLDNLWGVYLMLRDIQVAYKTQQVPNVISPYLPQELYDKMRVYKIHKGWFTIVNTLLSA 79
            ||..|.:....:..||..|..|...:| ::|.|:...:..|.:.|.|.|...|..|:|
Yeast    18 IISGFSIAQFSFESYLTYRQYQKLSET-KLPPVLEDEIDDETFHKSRNYSRAKAKFSI------- 74

  Fly    80 VILGIMELYFGFYAWLYGVAGKCALSKW-----MEHEACVSVIFVLLLSVYFWLKSVPAMIYESC 139
                     ||.   :|.:|.|....|:     :.|.| ||::.. :|.|.|.:.|..|   :|.
Yeast    75 ---------FGD---VYNLAQKLVFIKYDLFPKIWHMA-VSLLNA-VLPVRFHMVSTVA---QSL 122

  Fly   140 C----IKSLQPRPKPPWWSRICHFV-----------VDLVVGAMITTLVVV-----ALVYMFIGL 184
            |    :.||......| .|...|||           |.|.:..||.:|.:.     .::|:|:.:
Yeast   123 CFLGLLSSLSTLVDLP-LSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKI 186

  Fly   185 GPYAPLGLYLQSLILTMIVLLL----IPFMIHPFVGQSVPLENSNLRTQLEYLTRQVGFPMSQVR 245
            ....|.......::...:|.:|    ||..|.|...:..|||:..|:..:|.|..:||||:.::.
Yeast   187 FDKFPTDFLWYIMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIF 251

  Fly   246 IIRVHDPNTGSNAFFYGC-CCLKRIVIFDTLLLNRGKSDLSHLTAEELGRGLADPQVVAVVAHEL 309
            :|.....::.|||:|.|. ...||||:||| |:|...:|                ::.||:|||:
Yeast   252 VIDGSKRSSHSNAYFTGLPFTSKRIVLFDT-LVNSNSTD----------------EITAVLAHEI 299

  Fly   310 GHWRNGHFYKAIMAFQVHLILTILLFAFLFSHGPIYQAVGF----------PPGLQ---PTVIGC 361
            |||:..|....::..|:|..|...||..::.:...|...||          .|.:.   |.:||
Yeast   300 GHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIG- 363

  Fly   362 LIIFGFVLTPYMTLANFSMLSMTRCFEYQADRFAYQLGYGGELRQALLKLYADNLAFPVSDPCYS 426
            .::|..:|||......|.|..::|..|||||.:|.:|||...|.:||:.|...||:....||.||
Yeast   364 FMLFNDLLTPLECAMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYS 428

  Fly   427 SWNHTHPTMLDRLSRLE 443
            |::::|||:.:||:.|:
Yeast   429 SYHYSHPTLAERLTALD 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ste24b	NP_611174.1	Peptidase_M48_N	35..214	CDD:293100	48/207 (23%)
		HtpX	167..444	CDD:223575	92/300 (31%)
		Peptidase_M48	220..444	CDD:279743	80/238 (34%)
STE24	NP_012651.1	M48A_Zmpste24p_like	17..446	CDD:320702	135/472 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344117
Domainoid	1	1.000	179	1.000	Domainoid score	I716
eggNOG	1	0.900	-	-		E1_COG0501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1184
OMA	1	1.010	-	-		QHG61664
OrthoFinder	1	1.000	-	-		FOG0002450
OrthoInspector	1	1.000	-	-		otm46568
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10120
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.760