DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ste24b and ATSTE24

DIOPT Version :9

Sequence 1:	NP_611174.1	Gene:	ste24b / 36907	FlyBaseID:	FBgn0034175	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_567212.1	Gene:	ATSTE24 / 828209	AraportID:	AT4G01320	Length:	424	Species:	Arabidopsis thaliana

Alignment Length:	442	Identity:	122/442 - (27%)
Similarity:	232/442 - (52%)	Gaps:	33/442 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LAILYI--IIAFLVLDNLWGVYLMLRDIQVAYKTQQVPNVISPYLPQELYDKMRVYKIHKGWFTI 72
            :||.::  ::.|:::..::..||.||.: .|.|...:|..:...:.||.::|.|.|.:.|.:|..
plant     1 MAIPFMETVVGFMIVMYIFETYLDLRQL-TALKLPTLPKTLVGVISQEKFEKSRAYSLDKSYFHF 64

  Fly    73 VNTLLSAVILGIMELYFGFYAWLYGVAGKCALSKWMEHEACVSVIFVLLLSVYFW--LKSVPAMI 135
            |:..:: :::....|:||...|.:.::|.......::.|..:......|..|..|  :..:|..:
plant    65 VHEFVT-ILMDSAILFFGILPWFWKMSGAVLPRLGLDPENEILHTLSFLAGVMTWSQITDLPFSL 128

  Fly   136 YESCCIKSLQPRPKPPWWSRICHFVVDLVVGAMITTL----VVVALVYMFIGLGPYAPLGLYLQS 196
            |.:..|:|.....|...|.    |:.|::.|..::.:    :|.|::::....|||..:.|:...
plant   129 YSTFVIESRHGFNKQTIWM----FIRDMIKGTFLSVILGPPIVAAIIFIVQKGGPYLAIYLWAFM 189

  Fly   197 LILTMIVLLLIPFMIHPFVGQSVPLENSNLRTQLEYLTRQVGFPMSQVRIIRVHDPNTGSNAFFY 261
            .||:::::.:.|.:|.|...:..||.:.:||.::|.|...:.||:.::.::.....::.|||:.|
plant   190 FILSLVMMTIYPVLIAPLFNKFTPLPDGDLREKIEKLASSLKFPLKKLFVVDGSTRSSHSNAYMY 254

  Fly   262 GCCCLKRIVIFDTLLLNRGKSDLSHLTAEELGRGLADPQVVAVVAHELGHWRNGHFYKAIMAFQV 326
            |....||||::|||:......|                ::|||:|||||||:..|...:.:|.|:
plant   255 GFFKNKRIVLYDTLIQQCKNED----------------EIVAVIAHELGHWKLNHTTYSFIAVQI 303

  Fly   327 HLILTILLFAFLFSHGPIYQAVGFPPGLQPTVIGCLIIFGFVLTPYMTLANFSMLSMTRCFEYQA 391
            ...|....:..:.:...::::.||  ..||.:|| ||||...:.|...|.:|.:..::|.||:||
plant   304 LAFLQFGGYTLVRNSTDLFRSFGF--DTQPVLIG-LIIFQHTVIPLQHLVSFGLNLVSRAFEFQA 365

  Fly   392 DRFAYQLGYGGELRQALLKLYADNLAFPVSDPCYSSWNHTHPTMLDRLSRLE 443
            |.||.:|||..:||.||:||..:||:...:||.||:::::||.:::||..::
plant   366 DAFAVKLGYAKDLRPALVKLQEENLSAMNTDPLYSAYHYSHPPLVERLRAID 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ste24b	NP_611174.1	Peptidase_M48_N	35..214	CDD:293100	39/184 (21%)
		HtpX	167..444	CDD:223575	86/281 (31%)
		Peptidase_M48	220..444	CDD:279743	75/224 (33%)
ATSTE24	NP_567212.1	M48A_Zmpste24p_like	8..417	CDD:320702	120/433 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	187	1.000	Domainoid score	I974
eggNOG	1	0.900	-	-		E1_COG0501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61664
OrthoDB	1	1.010	-	-		D878143at2759
OrthoFinder	1	1.000	-	-		FOG0002450
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10120
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890