Protein Alignment ste24b and OMA1

DIOPT Version :10

• Sequence 1: NP_611174.1
• Gene: ste24b / 36907
• FlyBaseID: FBgn0034175
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_660286.1
• Gene: OMA1 / 115209
• HGNCID: 29661
• Length: 524
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 68/325 - (20%)
• Similarity: 97/325 - (29%)
• Gaps: 132/325 - (40%)

  Fly   180 MFIGLGPYAPLGLYLQSLILTMIVLLLIPFMIHPFVGQSVPL----ENSNLRTQLEYLTRQVGFP 240
            :|:||..:.          |..:|.......:.|..|:|..|    |...|.::|||......|.
Human   195 LFLGLSSFG----------LLFVVFYFTHLEVSPITGRSKLLLLGKEQFRLLSELEYEAWMEEFK 249

  Fly   241 ------------------------------MSQVR-IIRVHD---------PNTGSNAFFYGCCC 265
                                          :||:. :|.|.|         || |....|.|
Human   250 NDMLTEKDARYLAVKEVLCHLIECNKDVPGISQINWVIHVVDSPIINAFVLPN-GQMFVFTG--- 310

  Fly   266 LKRIVIFDTLLLNRGKSDLSHLTAEELGRGLADPQVVAVVAHELGHWRNGHFYKAIMAFQVHLIL 330
                      .|| ..:|:..|:              .::.||:.|...||  .|..|..||| |
Human   311 ----------FLN-SVTDIHQLS--------------FLLGHEIAHAVLGH--AAEKAGMVHL-L 347

  Fly   331 TILLFAFLFSHGPIYQAVGFPPGLQPTVIGCLIIFGFVLTPYMTLANFSMLSMTRCFEYQADR-F 394
            ..|...||                  |:|       :.:.|..:||.......::..||..:| :
Human   348 DFLGMIFL------------------TMI-------WAICPRDSLALLCQWIQSKLQEYMFNRPY 387

  Fly   395 AYQLGYGGELRQALL--KLYADNLAFPV------------SDPCYSSWNHTHPT------MLDRL 439
            :.:|....:....||  |..||..|..|            ..|....|..|||:      .||||
Human   388 SRKLEAEADKIGLLLAAKACADIRASSVFWQQMEFVDSLHGQPKMPEWLSTHPSHGNRVEYLDRL 452

  Fly   440  439
            Human   453  452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ste24b	NP_611174.1	M48A_Zmpste24p_like	14..444	CDD:320702	68/325 (21%)
OMA1	NP_660286.1	Cardiolipin-binding. /evidence=ECO:0000250|UniProtKB:Q9D8H7	148..167
		Stress-sensor region. /evidence=ECO:0000250|UniProtKB:Q9D8H7	165..195		68/325 (21%)
		M48C_Oma1_like	263..456	CDD:320690	53/247 (21%)