DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cbp53E and Calb1

DIOPT Version :10

Sequence 1:NP_476838.1 Gene:Cbp53E / 36905 FlyBaseID:FBgn0004580 Length:310 Species:Drosophila melanogaster
Sequence 2:NP_114190.1 Gene:Calb1 / 83839 RGDID:69340 Length:261 Species:Rattus norvegicus


Alignment Length:266 Identity:122/266 - (45%)
Similarity:174/266 - (65%) Gaps:22/266 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 LSANQFMDVWAHYDKDGNGYIEGTELDGFLREFVSSAN--ATDISPEAVTDTMLEELKSCFMEAY 97
            ::|:||.::|.|:|.||:||:||.||...::|.:.:..  ..::|||..|          |::.|
  Rat    11 ITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKT----------FVDQY 65

  Fly    98 DDNQDGKIDIRELAQLLPMEENFLLLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRD 162
            ....||||.|.|||.:||.|||||||||... |:|..||||.||:||||:||:||.:||||||:|
  Rat    66 GQRDDGKIGIVELAHVLPTEENFLLLFRCQQ-LKSCEEFMKTWRKYDTDHSGFIETEELKNFLKD 129

  Fly   163 LLKEAKKINDVSEDKLIEYTDTMLQVFDANKDGRLQLSEMAKLLPVKENFLCRQVFKGATKLTKE 227
            ||::|.|  .|.:.||.||||.||::||:|.||:|:|:|||:||||:||||.:  |:| .|:..:
  Rat   130 LLEKANK--TVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK--FQG-IKMCGK 189

  Fly   228 DIEKVFSLYDRDNSGTIENEELKGFLKDLLELVKKDDYDAQDLAAFEETIMRGVGTDKHGKISRK 292
            :..|.|.|||:|.:|.|:..||...||||.| ..|.:.|..:::.:::.||   .....||:.|.
  Rat   190 EFNKAFELYDQDGNGYIDENELDALLKDLCE-KNKQELDINNISTYKKNIM---ALSDGGKLYRT 250

  Fly   293 ELTMIL 298
            :|.:||
  Rat   251 DLALIL 256

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cbp53ENP_476838.1 EFh_HEF_CBN 40..301 CDD:320079 120/261 (46%)
EF-hand motif 40..68 CDD:320079 13/27 (48%)
EF-hand motif 89..118 CDD:320079 12/28 (43%)
EF-hand motif 135..164 CDD:320079 21/28 (75%)
EF-hand motif 181..210 CDD:320079 19/28 (68%)
EF-hand motif 228..257 CDD:320079 13/28 (46%)
EF-hand motif 273..301 CDD:320079 8/26 (31%)
Calb1NP_114190.1 Interaction with RANBP9. /evidence=ECO:0000250|UniProtKB:P05937 2..7
EFh_HEF_CB 16..259 CDD:320076 120/261 (46%)
EF-hand motif 16..44 CDD:320076 13/27 (48%)
EF-hand motif 57..86 CDD:320076 14/38 (37%)
EF-hand motif 102..131 CDD:320076 21/28 (75%)
EF-hand motif 146..175 CDD:320076 19/28 (68%)
EF-hand motif 190..219 CDD:320076 13/28 (46%)
EF-hand motif 231..259 CDD:320076 8/29 (28%)
Blue background indicates that the domain is not in the aligned region.

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