DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbp53E and calb1

DIOPT Version :9

Sequence 1:	NP_001286511.1	Gene:	Cbp53E / 36905	FlyBaseID:	FBgn0004580	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001072811.1	Gene:	calb1 / 780272	XenbaseID:	XB-GENE-951983	Length:	260	Species:	Xenopus tropicalis

Alignment Length:	265	Identity:	127/265 - (47%)
Similarity:	173/265 - (65%)	Gaps:	19/265 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KLSANQFMDVWAHYDKDGNGYIEGTELDGFLREFVSSANATDISPEAVTDTMLEELKSCFMEAYD 98
            ::||:||:::|.|||.||||:|||.||..|:.|...:.....:.        |.:....|::.|:
Frog    10 EISASQFLEIWRHYDTDGNGFIEGKELQNFILELQQARKKAGLD--------LSDQMKAFVDQYE 66

  Fly    99 DNQDGKIDIRELAQLLPMEENFLLLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRDL 163
            :|.||||.|.||||:||.||||||.||  ..|:||.|||:.||.||||:||:||.||||:||:||
Frog    67 NNTDGKIGIAELAQILPTEENFLLFFR--QQLKSSEEFMQSWRRYDTDHSGFIETDELKSFLKDL 129

  Fly   164 LKEAKKINDVSEDKLIEYTDTMLQVFDANKDGRLQLSEMAKLLPVKENFLCRQVFKGATKLTKED 228
            ||:|.|  ...|.||.|||.|||.:||.|.||:|.|:||:.||||:||||.:  |:| .|:..::
Frog   130 LKKANK--PCEETKLEEYTHTMLLMFDTNNDGKLGLTEMSMLLPVQENFLLK--FQG-VKMCGKE 189

  Fly   229 IEKVFSLYDRDNSGTIENEELKGFLKDLLELVKKDDYDAQDLAAFEETIMRGVGTDKHGKISRKE 293
            ..|||.|||:|.:|.|:..||...||||.:..|| |.|..:|:.::::||   .....||:.|.|
Frog   190 FNKVFELYDKDGNGYIDENELDDLLKDLCDKNKK-DLDINNLSTYKKSIM---ALSDGGKLYRTE 250

  Fly   294 LTMIL 298
            |.::|
Frog   251 LALVL 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbp53E	NP_001286511.1	EFh_HEF_CBN	40..301	CDD:320079	124/259 (48%)
		EF-hand motif	40..68	CDD:320079	16/27 (59%)
		EF-hand motif	89..118	CDD:320079	14/28 (50%)
		EF-hand motif	135..164	CDD:320079	20/28 (71%)
		EF-hand motif	181..210	CDD:320079	18/28 (64%)
		EF-hand motif	228..257	CDD:320079	14/28 (50%)
		EF-hand motif	273..301	CDD:320079	8/26 (31%)
calb1	NP_001072811.1	EFh_HEF	16..258	CDD:355006	124/259 (48%)
		EF-hand motif	16..44	CDD:320075	16/27 (59%)
		EF-hand motif	57..86	CDD:320075	14/28 (50%)
		EF-hand motif	101..130	CDD:320075	20/28 (71%)
		EF-hand motif	145..174	CDD:320075	18/28 (64%)
		EF-hand motif	189..218	CDD:320075	14/28 (50%)
		EF-hand motif	233..258	CDD:320075	8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3250
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415503at33208
OrthoFinder	1	1.000	-	-		FOG0003230
OrthoInspector	1	1.000	-	-		otm49057
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060