DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbp53E and TpnC73F

DIOPT Version :9

Sequence 1:	NP_001286511.1	Gene:	Cbp53E / 36905	FlyBaseID:	FBgn0004580	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001287091.1	Gene:	TpnC73F / 39916	FlyBaseID:	FBgn0010424	Length:	155	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	66/153 - (43%)	Gaps:	21/153 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 ESSVEFMKIWREYDTDNSGYIEADELKNFLRDLLKEAKKINDVSEDKLIEYTDTMLQVFDANKDG 195
            |......|.:..:|...:|.|..:.:.:.||       .:....:.|::|   .:::..|.:|.|
  Fly    11 EQIAVLQKAFNSFDHQKTGSIPTEMVADILR-------LMGQPFDKKILE---ELIEEVDEDKSG 65

  Fly   196 RLQLSEMAKLLPVKENFLCRQVFKGATKLTKEDIEKVFSLYDRDNSGTIENEELKGFLKDLLELV 260
            ||:..|..:|   ...|:   |.:.|..:.|| :.:.|.|||:..:|.|....||..||:|.:.:
  Fly    66 RLEFGEFVQL---AAKFI---VEEDAEAMQKE-LREAFRLYDKQGNGFIPTTCLKEILKELDDQL 123

  Fly   261 KKDDYDAQDLAAFEETIMRGVGT 283
            .:.:.|..    .||....|.||
  Fly   124 TEQELDIM----IEEIDSDGSGT 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbp53E	NP_001286511.1	EFh_HEF_CBN	40..301	CDD:320079	38/153 (25%)
		EF-hand motif	40..68	CDD:320079
		EF-hand motif	89..118	CDD:320079
		EF-hand motif	135..164	CDD:320079	6/28 (21%)
		EF-hand motif	181..210	CDD:320079	7/28 (25%)
		EF-hand motif	228..257	CDD:320079	10/28 (36%)
		EF-hand motif	273..301	CDD:320079	5/11 (45%)
TpnC73F	NP_001287091.1	PTZ00184	6..153	CDD:185504	38/153 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5029
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950