DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cbp53E and cmd-1

DIOPT Version :9

Sequence 1:	NP_001286511.1	Gene:	Cbp53E / 36905	FlyBaseID:	FBgn0004580	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_503386.1	Gene:	cmd-1 / 178614	WormBaseID:	WBGene00000552	Length:	149	Species:	Caenorhabditis elegans

Alignment Length:	172	Identity:	45/172 - (26%)
Similarity:	77/172 - (44%)	Gaps:	35/172 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 QFMDVWAHYDKDGNGYIEGTELDGFLREFVSSANATDISPEAVTDTMLEELKSCFMEAYDDNQDG 103
            :|.:.::.:||||:|.|...||...:|..  ..|.|    ||....|:.|:        |.:.:|
Worm    12 EFKEAFSLFDKDGDGTITTKELGTVMRSL--GQNPT----EAELQDMINEV--------DADGNG 62

  Fly   104 KIDIRELAQLLPMEENFL-LLFRFDNPLESSVEFMKIWREYDTDNSGYIEADELKNFLRDLLKEA 167
            .||..|          || ::.|.....:|..|..:.:|.:|.|.:|:|.|.||::.:.:|   .
Worm    63 TIDFPE----------FLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNL---G 114

  Fly   168 KKINDVSEDKLIEYTDTMLQVFDANKDGRLQLSEMAKLLPVK 209
            :|:.|       |..|.|::..|.:.||::...|...::..|
Worm   115 EKLTD-------EEVDEMIREADIDGDGQVNYEEFVTMMTTK 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cbp53E	NP_001286511.1	EFh_HEF_CBN	40..301	CDD:320079	45/171 (26%)
		EF-hand motif	40..68	CDD:320079	10/27 (37%)
		EF-hand motif	89..118	CDD:320079	5/28 (18%)
		EF-hand motif	135..164	CDD:320079	9/28 (32%)
		EF-hand motif	181..210	CDD:320079	7/29 (24%)
		EF-hand motif	228..257	CDD:320079
		EF-hand motif	273..301	CDD:320079
cmd-1	NP_503386.1	PTZ00184	1..149	CDD:185504	44/170 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910