Protein Alignment CG15614 and Gpr142

DIOPT Version :10

• Sequence 1: NP_611168.2
• Gene: CG15614 / 36899
• FlyBaseID: FBgn0034168
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001385802.1
• Gene: Gpr142 / 501735
• RGDID: 1559926
• Length: 348
• Species: Rattus norvegicus
• Alignment Length: 393
• Identity: 77/393 - (19%)
• Similarity: 131/393 - (33%)
• Gaps: 140/393 - (35%)

  Fly    34 PTVVLFVLYGLAVPTLSAFGLCTNFINAVVFMRPKMTPSAFSYLAALSWMDCISCLLITM----- 93
            |.:...||..|.:|.    .:.|..:.|.:.:|.| .|| :.||.||:..|.::.::|..
  Rat    49 PVIYYSVLLSLGLPV----NVLTTVVLARLAVRTK-KPS-YHYLLALTASDIVTQVVIVFIGFLL 107

  Fly    94 --TALSRSYFYSSPTWITYDYQWQTPLFGISTGGANL-----------ILACLSLDRFIYLSC-- 143
              ..|:|                |.|...:.|  ||:           |....::||:..| |
  Rat   108 QGAVLAR----------------QVPQAVVRT--ANILEFAANHASVWIAVLFTVDRYNAL-CRP 153

  Fly   144 -FKRNNGAPRFCRRKVARCIIVVAIGISIVVNMPYFF---VFYVSDSGTCHVTEFYYTNFYKVQN 204
             ..|...:|....|.:|     ..:.::::..:|:::   |:..:|..         :...|:..
  Rat   154 LRHRATSSPGRTHRAIA-----AVLSVTLLTGIPFYWWLDVWRDADPP---------STMDKLLK 204

  Fly   205 WFTFALLALLPAIFLVIGNGAIIIAFRK--------WTKQSRICQANNPAANSRTTAKRYQHQMK 261
            |....::..:|....::.|.|||:..||        |..:|........:..:...|.|
  Rat   205 WAHCLIVYFIPCNVFLVTNSAIILRLRKRGQRGLQPWMSKSTAILLGVTSLFALLWAPR------ 263

  Fly   262 LTISIVIVITLYLFGELPAHMTSRKSSLNLLFGGDANKVDDSFIEQLEVICITLNALQLSLNIV- 325
                  |.:.||.....|.|...|                                :.|:|:|.
  Rat   264 ------ISVMLYHLYVAPVHRDWR--------------------------------VHLALDIAN 290

  Fly   326 VYAVINPSFMPEFFLCLKGTSDVCFGLCCF--RAVRRTWRR--------CQDKRKQKATAEERVV 380
            :.|::|.:              |.|||.||  :..|.|.|:        |..|.:.|.|..|.|:
  Rat   291 MLAMLNTA--------------VNFGLYCFISKTFRATVRQVIQDVHMSCALKSQPKGTVTELVL 341

  Fly   381 SSV 383
            .||
  Rat   342 KSV 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15614	NP_611168.2	7tmA_FMRFamide_R-like	40..338	CDD:410630	59/330 (18%)
		TM helix 1	41..67	CDD:410630	5/25 (20%)
		TM helix 2	73..98	CDD:410630	7/31 (23%)
		TM helix 3	112..142	CDD:410630	8/40 (20%)
		TM helix 4	157..177	CDD:410630	1/19 (5%)
		TM helix 5	200..225	CDD:410630	4/24 (17%)
		TM helix 6	257..293	CDD:410630	6/35 (17%)
		TM helix 7	306..331	CDD:410630	4/25 (16%)
Gpr142	NP_001385802.1	7tm_GPCRs	47..315	CDD:475119	67/362 (19%)
		TM helix 1	49..73	CDD:410628	6/27 (22%)
		TM helix 2	83..105	CDD:410628	6/21 (29%)
		TM helix 3	122..144	CDD:410628	4/23 (17%)
		TM helix 4	167..183	CDD:410628	2/20 (10%)
		TM helix 5	201..224	CDD:410628	3/22 (14%)
		TM helix 6	246..268	CDD:410628	3/33 (9%)
		TM helix 7	283..308	CDD:410628	11/38 (29%)