Protein Alignment CG15614 and GHSR

DIOPT Version :10

• Sequence 1: NP_611168.2
• Gene: CG15614 / 36899
• FlyBaseID: FBgn0034168
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_940799.1
• Gene: GHSR / 2693
• HGNCID: 4267
• Length: 366
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 64/340 - (18%)
• Similarity: 127/340 - (37%)
• Gaps: 80/340 - (23%)

  Fly    40 VLYGLAVPTLSAF--GLCTNFINAVVFMR-PKMTPSAFSYLAALSWMDCISCLLITMTALSRSYF 101
            :|.|:....::.|  |:..|.:..:|..| .::..:...||:::::.|    |||         |
Human    42 LLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSD----LLI---------F 93

  Fly   102 YSSPTWITYDYQWQTPLFG---------IS---TGGANLILACLSLDRFIYLSCFKRNNGAPRFC 154
            ...|..:...:|::...||         :|   |....|.:..||::|: :..||.        .
Human    94 LCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERY-FAICFP--------L 149

  Fly   155 RRKV------ARCIIVVAIGISIVVNMPYFFVFYVS--------DSGTCHVTEF-YYTNFYKVQN 204
            |.||      .:.:|.|...::.....|.|.:..|.        |:..|..||| ..:....|..
Human   150 RAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMV 214

  Fly   205 W----FTFALLALLPAIFLVIGNGAIIIAFRKWTKQ--SRICQANNPAANSRTTAKRYQHQMKLT 263
            |    |.|..:..|..::.:||.       :.|.::  ..:..|:....|.:.|.|
Human   215 WVSSIFFFLPVFCLTVLYSLIGR-------KLWRRRRGDAVVGASLRDQNHKQTVK--------- 263

  Fly   264 ISIVIVITLYLFGELPAHMTSRKSSLNLLFGGDANKVDDSFIEQ-LEVICITLNALQLSLNIVVY 327
             .:.:|:..::...||.|:.....|.:.    :...::.:.|.| ..::...|..|..::|.::|
Human   264 -MLAVVVFAFILCWLPFHVGRYLFSKSF----EPGSLEIAQISQYCNLVSFVLFYLSAAINPILY 323

  Fly   328 AVINPSFMPEFFLCL 342
            .:::..:....|..|
Human   324 NIMSKKYRVAVFRLL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15614	NP_611168.2	7tmA_FMRFamide_R-like	40..338	CDD:410630	62/334 (19%)
		TM helix 1	41..67	CDD:410630	7/28 (25%)
		TM helix 2	73..98	CDD:410630	6/24 (25%)
		TM helix 3	112..142	CDD:410630	9/41 (22%)
		TM helix 4	157..177	CDD:410630	4/25 (16%)
		TM helix 5	200..225	CDD:410630	7/28 (25%)
		TM helix 6	257..293	CDD:410630	5/35 (14%)
		TM helix 7	306..331	CDD:410630	5/25 (20%)
GHSR	NP_940799.1	7tmA_GHSR	44..334	CDD:320259	61/332 (18%)
		TM helix 1	44..71	CDD:320259	5/26 (19%)
		TM helix 2	78..103	CDD:320259	8/37 (22%)
		TM helix 3	116..146	CDD:320259	6/30 (20%)
		TM helix 4	158..180	CDD:320259	3/21 (14%)
		TM helix 5	209..238	CDD:320259	7/35 (20%)
		TM helix 6	256..286	CDD:320259	7/39 (18%)
		TM helix 7	302..327	CDD:320259	5/24 (21%)