Protein Alignment CG15614 and Gpr142

DIOPT Version :10

• Sequence 1: NP_611168.2
• Gene: CG15614 / 36899
• FlyBaseID: FBgn0034168
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001333701.1
• Gene: Gpr142 / 217302
• MGIID: 2668437
• Length: 371
• Species: Mus musculus
• Alignment Length: 399
• Identity: 80/399 - (20%)
• Similarity: 142/399 - (35%)
• Gaps: 141/399 - (35%)

  Fly    32 RRPTV--VLFVLYGLAVPTLSAFGLCTNFINAVVFMR--PKMTPSAFSYLAALSWMDCISCLLIT 92
            |.|.|  ::.|:|   ...|.:.||..|.:.:|...|  .:....::.||.||:..|.::.::|.
Mouse    63 RSPCVAGIIPVIY---YSVLLSLGLPVNVLTSVALARLAARTRKPSYHYLLALTASDIVTQVIIV 124

  Fly    93 M-------TALSRSYFYSSPTWITYDYQWQTPLFGISTGGANL-----------ILACLSLDRFI 139
            .       ..|:|                |.|...:.|  ||:           |....::||:.
Mouse   125 FVGFLLQGAVLAR----------------QVPQAVVRT--ANILEFAANHASVWIAVLFTVDRYN 171

  Fly   140 YLSC---FKRNNGAPRFCRRKVARCIIVVAIGISIVVNMPYFF---VFYVSDSGTCHVTEFYYTN 198
            .| |   ..|...:|....|.:|     ..||::::..:|:::   |:..:|..         :.
Mouse   172 AL-CRPLRHRATSSPGRTHRAIA-----AVIGVTLLTGIPFYWWLDVWRDADPP---------ST 221

  Fly   199 FYKVQNWFTFALLALLPAIFLVIGNGAIIIAFRKWTKQSRICQANNPAANSRTTAKRYQHQMKLT 263
            ..|:..|....::..:|....::.|.|||:..||     |..:...|.. |::||      :.|.
Mouse   222 MDKLLKWAHCLIVYFIPCNVFLVTNSAIILRLRK-----RGQRGLRPLV-SKSTA------ILLG 274

  Fly   264 ISIV--------IVITLYLFGELPAHMTSRKSSLNLLFGGDANKVDDSFIEQLEVICITLNALQL 320
            ::.:        |::.||.....|.|...|                                :.|
Mouse   275 VTSLFALLWAPRIIVMLYHLYVAPVHRDWR--------------------------------VHL 307

  Fly   321 SLNIV-VYAVINPSFMPEFFLCLKGTSDVCFGLCCF--RAVRRTWRR--------CQDKRKQKAT 374
            :|:|. :.|::|              ::|.|||.||  :..|.|.|:        |..|.:.|.|
Mouse   308 ALDIANMLAMLN--------------TEVNFGLYCFISKTFRATVRQVICDVHMACALKSQPKQT 358

  Fly   375 AEERVVSSV 383
            ..|.::.||
Mouse   359 VVELMLKSV 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15614	NP_611168.2	7tmA_FMRFamide_R-like	40..338	CDD:410630	61/332 (18%)
		TM helix 1	41..67	CDD:410630	7/27 (26%)
		TM helix 2	73..98	CDD:410630	7/31 (23%)
		TM helix 3	112..142	CDD:410630	8/40 (20%)
		TM helix 4	157..177	CDD:410630	3/19 (16%)
		TM helix 5	200..225	CDD:410630	4/24 (17%)
		TM helix 6	257..293	CDD:410630	7/43 (16%)
		TM helix 7	306..331	CDD:410630	4/25 (16%)
Gpr142	NP_001333701.1	7tm_GPCRs	70..338	CDD:475119	68/361 (19%)
		TM helix 1	72..96	CDD:320257	7/26 (27%)
		TM helix 2	106..128	CDD:320257	6/21 (29%)
		TM helix 3	145..167	CDD:320257	4/23 (17%)
		TM helix 4	190..206	CDD:320257	4/20 (20%)
		TM helix 5	224..247	CDD:320257	3/22 (14%)
		TM helix 6	269..291	CDD:320257	4/27 (15%)
		TM helix 7	306..331	CDD:320257	11/38 (29%)