Protein Alignment CG15614 and Gpr139

DIOPT Version :10

• Sequence 1: NP_611168.2
• Gene: CG15614 / 36899
• FlyBaseID: FBgn0034168
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001019309.1
• Gene: Gpr139 / 209776
• MGIID: 2685341
• Length: 345
• Species: Mus musculus
• Alignment Length: 407
• Identity: 76/407 - (18%)
• Similarity: 131/407 - (32%)
• Gaps: 150/407 - (36%)

  Fly    49 LSAFGLCTNFINAVVFMR--PKMTPSAFSYLAALSWMDCISCLLIT------------------- 92
            |...||..|.:..::..:  .:...|:::||.||:..|.:....|.
Mouse    28 LLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFILTMQMPLIP 92

  Fly    93 ---MTALSRSYFYSSPTWITYDYQWQTPLFGISTGGANLILACLSLDRFIYLSC--FKRNNGAPR 152
               :..|..|..::| .|||..                     |::||:|.: |  .|.:..:..
Mouse    93 DKIIEVLEFSSIHTS-IWITVP---------------------LTVDRYIAV-CHPLKYHTVSYP 134

  Fly   153 FCRRKVARCIIVVAIGISIVVNMPYFF---VFYVSDSGTCHVTEFYY-TNFYKVQNWFTFALLAL 213
            ...|||...:.:..    .:.::||::   ::          ||.|. |:.:.|..|.....:.|
Mouse   135 ARTRKVILSVYITC----FLTSIPYYWWPNIW----------TEDYISTSMHHVLVWIHCFTVYL 185

  Fly   214 LPAIFLVIGNGAIIIAFRKWTKQSRICQANNPAANSRTTAKRYQHQMKLTISIVIVITLYLFGEL 278
            :|.....|.|..|:...|:         .:|......:|.|        |.:|:..|| .:|..|
Mouse   186 VPCSIFFILNSIIVYKLRR---------KSNFRLRGYSTGK--------TTAILFTIT-SIFATL 232

  Fly   279 PA--------HMTSRKSSLNLLFGGDANKVDDSFIEQLEVICITLNALQLSLNIVVYAVINPSFM 335
            .|        |          |:|..        |:...::.|.|:...:      .|::|.:.
Mouse   233 WAPRIIMILYH----------LYGAP--------IQNPWLVHIMLDVANM------LALLNTAI- 272

  Fly   336 PEFFLCLKGTSDVCFGLCCFR----AVRRTWRRCQDKRKQKATAEERVVSSVTPQHLPPDEALPC 396
             .|||       .||....||    |..:...:||.:..|..|.....::|
Mouse   273 -NFFL-------YCFISKRFRTMAAATLKALFKCQKQPVQFYTNHNFSITS-------------- 315

  Fly   397 GCESWASDSSCKINAHC 413
              ..|.|.:    |:||
Mouse   316 --SPWISPA----NSHC 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15614	NP_611168.2	7tmA_FMRFamide_R-like	40..338	CDD:410630	58/326 (18%)
		TM helix 1	41..67	CDD:410630	4/19 (21%)
		TM helix 2	73..98	CDD:410630	7/46 (15%)
		TM helix 3	112..142	CDD:410630	4/29 (14%)
		TM helix 4	157..177	CDD:410630	2/19 (11%)
		TM helix 5	200..225	CDD:410630	6/24 (25%)
		TM helix 6	257..293	CDD:410630	8/43 (19%)
		TM helix 7	306..331	CDD:410630	3/24 (13%)
Gpr139	NP_001019309.1	7tmA_GPR139	19..288	CDD:320585	65/347 (19%)
		TM helix 1	20..46	CDD:320585	4/17 (24%)
		TM helix 2	54..79	CDD:320585	6/24 (25%)
		TM helix 3	93..123	CDD:320585	10/52 (19%)
		TM helix 4	135..155	CDD:320585	3/23 (13%)
		TM helix 5	172..197	CDD:320585	6/24 (25%)
		TM helix 6	213..245	CDD:320585	10/50 (20%)
		TM helix 7	256..281	CDD:320585	9/39 (23%)