Protein Alignment CG15614 and sqr-1

DIOPT Version :10

• Sequence 1: NP_611168.2
• Gene: CG15614 / 36899
• FlyBaseID: FBgn0034168
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_498999.3
• Gene: sqr-1 / 186597
• WormBaseID: WBGene00010315
• Length: 428
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 92/445 - (20%)
• Similarity: 159/445 - (35%)
• Gaps: 116/445 - (26%)

  Fly    24 SDECIFQRRRPTVVLF---VLYGLAVPTLSAFGLCTNFINAVVFMRPKMTPSAFSYLAALSWMDC 85
            :|.|:..|:....|..   ||.|..:|.|..||:..|.:|..|.:.|.:...:...||.|:..|.
 Worm    13 TDICLTDRQMSLSVSSTEGVLIGTIIPILVLFGISGNILNLTVLLAPNLRTRSNQLLACLAVADI 77

  Fly    86 ISCLLITMTALSRSYFYSSPTWI-----TYDYQ------WQTPLFGISTGGANLILACLSLDRFI 139
            :|.::|...:::....:.:..|.     .|.:|      |       |...|..::..:.|:|.|
 Worm    78 VSLVVILPHSMAHYETFETALWFRKFYGKYKFQIIAMTNW-------SIATATWLVFVICLERLI 135

  Fly   140 Y----LSCFKRNNGAPRFCRRKVARCIIVVAIGISIVVNMPYFFVFYVSDSGTCHVTEFYYTNFY 200
            .    ||..|:   |..|..|.|          ::|:|...:....|...|..|....|.....|
 Worm   136 IIKYPLSVRKQ---AKFFTPRNV----------VTIIVVTTFILTSYNHVSHACAEKLFCNGTQY 187

  Fly   201 KV-------QNWF---------------------TFALLALLPAIFLVIGNGAIIIAFRKWTKQS 237
            .|       :.||                     ....:.|:|.:.::|.|..:|:..|:.||..
 Worm   188 HVACLGIDSERWFRNEPNPNSEFMKSVVRVAPQVNAIFVVLIPVVLVIIFNVMLILTLRQRTKLF 252

  Fly   238 RICQANNPAANSRTTAKRYQHQMKLTISIVIVITLYLFGELPAHMTSRKSSLNLLFGGDANKVDD 302
            .  .:.....:|:.|..:.:.:.|:||::..::|.:...:.|:...:..||.          |..
 Worm   253 E--PSKTIRGDSQFTQLQSKTEHKVTITVTAIVTCFTITQSPSAFVTFLSSY----------VHR 305

  Fly   303 SFIEQLEVICITLNALQLSLNIVVYAVINPSFMPEFFLCLKGTSDVCFGLCCFRAVRRTWRRCQD 367
            .:: .|..||..|..|..:||.|::.:.:.||.....:..|            :.:.|
 Worm   306 DWV-TLSAICTILVVLGKALNFVLFCLSSASFRQRLLMQTK------------QGILR------- 350

  Fly   368 KRKQKATAEERVVSSVTPQHLPPDEALPCG----------CESWASDSSCKINAH 412
                |:|   |.||.||...:..| :||..          .|...|.|||.:..:
 Worm   351 ----KST---RTVSMVTSSTVVVD-SLPESRKKSRVAMEMIERRTSASSCLVGGN 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15614	NP_611168.2	7tmA_FMRFamide_R-like	40..338	CDD:410630	71/340 (21%)
		TM helix 1	41..67	CDD:410630	9/25 (36%)
		TM helix 2	73..98	CDD:410630	6/24 (25%)
		TM helix 3	112..142	CDD:410630	7/39 (18%)
		TM helix 4	157..177	CDD:410630	3/19 (16%)
		TM helix 5	200..225	CDD:410630	8/52 (15%)
		TM helix 6	257..293	CDD:410630	7/35 (20%)
		TM helix 7	306..331	CDD:410630	8/24 (33%)
sqr-1	NP_498999.3	7tmA_FMRFamide_R-like	32..340	CDD:410630	71/340 (21%)
		TM helix 1	33..59	CDD:410630	9/25 (36%)
		TM helix 2	65..90	CDD:410630	6/24 (25%)
		TM helix 3	108..138	CDD:410630	7/36 (19%)
		TM helix 4	150..170	CDD:410630	5/29 (17%)
		TM helix 5	215..240	CDD:410630	4/24 (17%)
		TM helix 6	270..300	CDD:410630	5/29 (17%)
		TM helix 7	308..333	CDD:410630	8/25 (32%)