Protein Alignment inaC and Prkcq

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001263650.1
• Gene: Prkcq / 85420
• RGDID: 620968
• Length: 707
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 241/669 - (36%)
• Similarity: 341/669 - (50%)
• Gaps: 133/669 - (19%)

  Fly    57 RKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKC 121
            |:||:|:..:..|..|.|...||..||:|..|.:|:||..|||:||.:|...||:||...|:.||
  Rat   145 RRGAIKQAKVHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKC 209

  Fly   122 PG-----KDTDFDADCAKV--KHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQ 179
            .|     ::|.|..:..|:  .|.:....|.:||||:.||.||.|:|.||:||:.|.:||||.||
  Rat   210 TGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQ 274

  Fly   180 ETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTK 244
            ..|..:||     :..||:              .||..:|                ...:..||.
  Rat   275 TKVANLCG-----INQKLM--------------AEALAMI----------------ESTQQARTL 304

  Fly   245 KKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGW 309
            :.::.|             |...|        ||:             ||..|::. :..|
  Rat   305 RDSEHI-------------FREGP--------IEI-------------SFPRSIKS-ETRP---- 330

  Fly   310 YKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKR--------RMDNKDM------PH-N 359
                          |||..                |.:|.        .:|..|.      |. |
  Rat   331 --------------PCVPT----------------PGKKEPQGICWESPLDGADKTAQPPEPEVN 365

  Fly   360 MSKRDM---IRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKK 421
            :.:..:   ::..||...|::||||||||.|||.:.|.:.:|:|.|:|||::..||:|..|.||:
  Rat   366 LQRASLQLKLKIDDFILHKMLGKGSFGKVFLAEFKRTKQFFAIKALKKDVVLMDDDVECTMVEKR 430

  Fly   422 ILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFL 486
            :|:|:...|||..|...|||.:.|||||||..|||||||:|...:|..|.|.|||.|:.:.|.||
  Rat   431 VLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFL 495

  Fly   487 HERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAA 551
            |.:.|:||||||||||||.:||:|:.|||:.||.:.....|.||||||:|:||||:....|:.:.
  Rat   496 HSKGIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSV 560

  Fly   552 DWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAG 616
            |||||||||:|.:.||:||.|.||..:|.:|:.....:|:....||.|::.....::|..|||
  Rat   561 DWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLG-- 623

  Fly   617 RYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNL 681
              .|.:|..||.||.::|::.|..|::||.:|.:|...|.||||..|..||..|:..|:..:.::
  Rat   624 --VRGDIRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDKEFLSEKPRLSFADRALINSM 686

  Fly   682 DQNDFIGFSFMNPEFITII 700
            |||.|..|||:||...|:|
  Rat   687 DQNMFSNFSFINPGMETLI 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	24/51 (47%)
		C1	137..190	CDD:412127	26/52 (50%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	16/129 (12%)
		STKc_PKC	375..692	CDD:270722	150/316 (47%)
Prkcq	NP_001263650.1	C1_nPKC_theta-like_rpt1	153..213	CDD:410384	26/59 (44%)
		C1_nPKC_theta-like_rpt2	232..281	CDD:410387	24/48 (50%)
		STKc_nPKC_theta	374..704	CDD:270770	155/333 (47%)