Protein Alignment inaC and KIN82

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_010015.3
• Gene: KIN82 / 850453
• SGDID: S000000687
• Length: 720
• Species: Saccharomyces cerevisiae
• Alignment Length: 593
• Identity: 169/593 - (28%)
• Similarity: 246/593 - (41%)
• Gaps: 135/593 - (22%)

  Fly   173 NVHHACQETVPP---MCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDP----Y 230
            |||.....|:.|   :|... :|:.|......||    ...|       :|.|.:.|..|    |
Yeast   142 NVHSTTSSTLIPNEAICSTP-NEISGSSSPDAEL----FTFD-------MPTDPSSFHTPSSPSY 194

  Fly   231 IAVQMHPDRSGRTKKKTKTIQK-NLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSF 294
            ||            |.::.:.. :||.: ||  ..|||...|            :.|.|   ||.
Yeast   195 IA------------KDSRNLSNGSLNDI-NE--NEELQNFHR------------KISEN---GSA 229

  Fly   295 S-FSLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDE------------VRHDR--- 343
            | .:...|...|:|...|   ..|.....||    .|...|||..            :|.|.
Yeast   230 SPLANLSLSNSPIDSPRK---NSETRKDQIP----MNITPRLRRAASEPFNTAKDGLMREDYIAL 287

  Fly   344 ----------RPNEKRRMDNKDMPHNMSKRDM-IRAADFNFVKVIGKGSFGKVLLAERRGTDELY 397
                      .|...||:..|...:..  :|: :....|..::::|:|..|||.|...|.|::::
Yeast   288 KQPPSLGDIVEPRRSRRLRTKSFGNKF--QDITVEPQSFEKIRLLGQGDVGKVYLVRERDTNQIF 350

  Fly   398 AVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQ 462
            |:|||.|..:|:...::..:.|::|||.|.. ||:|:::..|||.|.|:..||||.||:....:|
Yeast   351 ALKVLNKHEMIKRKKIKRVLTEQEILATSDH-PFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQ 414

  Fly   463 --QYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQ 525
              :.....|..|.|||.||..||.:||....||||||.:||||...|||.|.||.||.:....::
Yeast   415 TRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKK 479

  Fly   526 ------------------TTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEG 572
                              .|.:|.||..|:|||::..:.::.|.|||:.|:|::|.:.|..||:|
Yeast   480 PTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKG 544

  Fly   573 DDETTVFRNIKDKKAVFP--KHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWD 635
            |:....|.||..|...||  |..|....|:|...|.|....|||: :....:|..||||:.|.|.
Yeast   545 DNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGS-KSGAADIKRHPFFKKVQWS 608

  Fly   636 KAEACEMEPPIKPMI--------------KH--RKDISNFDDAFTKEKT-------DLTPTDKLF 677
            ...  ..:||:.|.:              ||  |..:|..:.....||.       :..|.....
Yeast   609 FLR--NQDPPLIPALNDNGCELPFILSCNKHPKRNSVSEQETKMFCEKVANDDEIDEADPFHDFN 671

  Fly   678 MMNLDQND 685
            .|:|.:.|
Yeast   672 SMSLTKKD 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127	6/19 (32%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	30/135 (22%)
		STKc_PKC	375..692	CDD:270722	118/356 (33%)
KIN82	NP_010015.3	STKc_phototropin_like	322..623	CDD:270726	109/304 (36%)