Protein Alignment inaC and prkca

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_031750036.1
• Gene: prkca / 780209
• XenbaseID: XB-GENE-5942870
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 663
• Identity: 342/663 - (51%)
• Similarity: 464/663 - (69%)
• Gaps: 26/663 - (3%)

  Fly    57 RKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKC 121
            ||||:::|.:..|..|:|..||||.||:|.||.|||||||||||||:.|.|.:|::|.:||.|.|
 Frog    26 RKGALRQKNVHEVKNHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFTC 90

  Fly   122 PGKDTDFDADCAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMC 186
            ||.|...|.|..:.||.:...||.:|||||.||.||:|:.|||:|||.|::|||..|...||.:|
 Frog    91 PGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCETCDMNVHKVCVINVPSLC 155

  Fly   187 GADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQ 251
            |.|.:|.||::.|..|:||:.|.|.:::|.||||||.||.||||:.:::.||....:||||||.:
 Frog   156 GMDHTEKRGRIYLKAEVKGDVLNVIVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKKKTKTFR 220

  Fly   252 KNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQV 316
            ..|||.:||.|||:|:|.|:|:||.:|:||||||:|||||||.||.:.||.|.|..||||.|:|.
 Frog   221 STLNPQWNECFTFKLKPTDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPACGWYKLLNQE 285

  Fly   317 EGEHYNIPCVD-----------AFNDIARLRDEVRHDRRPNEKRRM---DNKDMPHNMSKR---- 363
            |||:||:|..:           .|......||:|   ..|.:|.::   .||.:.....:|
 Frog   286 EGEYYNVPIPEEEDDGNIELRQKFEGTVPARDKV---VPPVQKAKLGPAGNKVISPTDERRPYVP 347

  Fly   364 ----DMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILA 424
                |.:|..||:|:.|:||||||||:||||:|.|||:|:|:|:|||:||.||:|..|.||::||
 Frog   348 SNNIDSVRLTDFSFLMVLGKGSFGKVMLAERKGADELFAIKILKKDVVIQDDDVECTMVEKRVLA 412

  Fly   425 LSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHER 489
            |.|:||||..:||||||:|||:|||||..|||||||:||.|:|||..|:|||.|:::.|||||::
 Frog   413 LQGKPPFLTHLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISVGLFFLHKK 477

  Fly   490 DIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWW 554
            .|:||||||||::||.|||:|:.|||:.||.:.:..|||||||||:|:||||::|.||..:.|||
 Frog   478 GIVYRDLKLDNVMLDSEGHIKIADFGMCKEHMVDGVTTRTFCGTPDYIAPEIIAYQPYGRSVDWW 542

  Fly   555 SFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYA 619
            ::||||:|.:|||.||:|:||..:|::|.:....:||..|.||:.|....:||.|..|||.|...
 Frog   543 AYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSMSKEAVSICKGLMTKHPVKRLGCGPEG 607

  Fly   620 RQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQN 684
            .::|..|.|||.:||:|.:..|::||.||.: ..|...|||..||:.:..|||.|:|.:.|:||.
 Frog   608 ERDIREHTFFRRIDWEKLQNREIQPPFKPKV-CGKGAENFDKFFTRGQPVLTPPDQLVIANIDQA 671

  Fly   685 DFIGFSFMNPEFI 697
            ||.|||::||:|:
 Frog   672 DFEGFSYINPQFV 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	32/51 (63%)
		C1	137..190	CDD:412127	28/52 (54%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	74/129 (57%)
		STKc_PKC	375..692	CDD:270722	176/316 (56%)
prkca	XP_031750036.1	C1_cPKC_rpt1	39..96	CDD:410383	35/56 (63%)
		C1_cPKC_rpt2	106..159	CDD:410386	28/52 (54%)
		C2_PKC_alpha_gamma	163..293	CDD:175992	74/129 (57%)
		STKc_cPKC_alpha	348..688	CDD:270766	184/338 (54%)