DRSC/TRiP Functional Genomics Resources

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Protein Alignment inaC and AURKC

DIOPT Version :10

Sequence 1:NP_476863.1 Gene:inaC / 36897 FlyBaseID:FBgn0004784 Length:700 Species:Drosophila melanogaster
Sequence 2:NP_001015878.1 Gene:AURKC / 6795 HGNCID:11391 Length:309 Species:Homo sapiens


Alignment Length:82 Identity:20/82 - (24%)
Similarity:27/82 - (32%) Gaps:24/82 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 KTLLFNQTVVGIPTAYIAFNLSRNGVPPP-----RALPSAFTVVRDFAVCIT------------- 79
            |.||..|..:|..|....|      :|.|     .:||||.....:|....|             
Human   887 KLLLCTQKELGQQTGLPVF------LPSPAGNIFSSLPSASAESGNFQTSSTKSDATVSSDNMDR 945

  Fly    80 LWEITFYYSHRLLHSRF 96
            ||:.:...|.:..|..|
Human   946 LWDSSQPISSQQTHLEF 962

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaCNP_476863.1 C1_cPKC_nPKC_rpt1 71..123 CDD:410342 7/39 (18%)
C1 137..190 CDD:412127
C2_PKC_alpha_gamma 194..324 CDD:175992
STKc_PKC 375..692 CDD:270722
AURKCNP_001015878.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33
STKc_Aurora-B_like 36..305 CDD:271019
Interaction with BIRC5. /evidence=ECO:0000269|PubMed:27332895 292..309
Blue background indicates that the domain is not in the aligned region.

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