DRSC/TRiP Functional Genomics Resources

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Protein Alignment inaC and AURKA

DIOPT Version :10

Sequence 1:NP_476863.1 Gene:inaC / 36897 FlyBaseID:FBgn0004784 Length:700 Species:Drosophila melanogaster
Sequence 2:NP_001411347.1 Gene:AURKA / 6790 HGNCID:11393 Length:437 Species:Homo sapiens


Alignment Length:83 Identity:22/83 - (26%)
Similarity:31/83 - (37%) Gaps:17/83 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 QTVVGIPTAYIAFNLS---RNGVPPPRALPSAFTVVRDF--AVCITLWEITFYYSHRLLHSRFFY 98
            :||.|:.|......||   ||.:|     ..|:....|:  |||     ..|.:|..:..:.  .
Human   289 RTVFGVTTVLTMTTLSISARNSLP-----KVAYATAMDWFIAVC-----YAFVFSALIEFAT--V 341

  Fly    99 KYVHKKHHEWTSPVALAA 116
            .|..|:...|....||.|
Human   342 NYFTKRGWAWDGKKALEA 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaCNP_476863.1 C1_cPKC_nPKC_rpt1 71..123 CDD:410342 12/48 (25%)
C1 137..190 CDD:412127
C2_PKC_alpha_gamma 194..324 CDD:175992
STKc_PKC 375..692 CDD:270722
AURKANP_001411347.1 STKc_Aurora-A 161..418 CDD:271018 22/83 (27%)
Blue background indicates that the domain is not in the aligned region.

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