Protein Alignment inaC and Rps6ka6

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_080225.2
• Gene: Rps6ka6 / 67071
• MGIID: 1914321
• Length: 860
• Species: Mus musculus
• Alignment Length: 485
• Identity: 170/485 - (35%)
• Similarity: 246/485 - (50%)
• Gaps: 42/485 - (8%)

  Fly   229 PYIAVQMHP--DRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRL-------LIEVWD-WD 283
            |.:.:..:|  .||..|:::|.:.:.:..|.........|.|.....|.       ...|.| ||
Mouse    44 PVVPLLRYPRLARSAVTQRETWSFEDDQEPAQQTGCMLVLGPGSFFSRAPEAAMLPFAPVEDPWD 108

  Fly   284 RTSRNDFMGSFSFSLEELQKEP-VDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNE 347
            :.....| ||.|.|      || |....|..:.|..||..    ...||: ::.||...:..|..
Mouse   109 QEDMEVF-GSTSSS------EPQVVFTMKNAATVMREHER----KEVNDL-KMVDEPMEEGEPVS 161

  Fly   348 KRRMD-NKDMPHNMSKRDMIRAAD---FNFVKVIGKGSFGKVLLAERR-GTD--ELYAVKVLRKD 405
            .||.: .|::|.....::....||   |:.:||:|:||||||.|..:: |.|  :|||:|||||.
Mouse   162 CRREELVKEIPITQHVKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKA 226

  Fly   406 VIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKES 470
            .:...|.:...| |:.|| :....||:|.:|..|||..:|:.::::.:|||:...:.:...|.|.
Mouse   227 SLKVRDRVRTKM-ERDIL-VEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEE 289

  Fly   471 VAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPN 535
            ...||..|:|:||..||...|:|||||.:|||||..||:||.|||||||.|.:.:...:||||..
Mouse   290 DVKFYLAELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVE 354

  Fly   536 YMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDI 600
            |||||:|:...:|.:|||||:|||:||.:.|..||:|.|.......|...|...|:..|.||..:
Mouse   355 YMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSL 419

  Fly   601 ITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTK 665
            :.....:.|.||||:  ...:|:..|.||.::||:|....|::||.:|......|...||..||.
Mouse   420 LRMLFKRNPANRLGS--EGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTA 482

  Fly   666 EKTDLTPTDKLFM---MNLDQNDFIGFSFM 692
            :    ||.|...:   .|..|. |.||||:
Mouse   483 K----TPKDSPGLPASANAHQL-FKGFSFV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992	26/105 (25%)
		STKc_PKC	375..692	CDD:270722	131/322 (41%)
Rps6ka6	NP_080225.2	STKc_RSK_N	193..507	CDD:270734	131/322 (41%)
		STKc_RSK_C	542..828	CDD:270993