DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaC and sgk2a

DIOPT Version :9

Sequence 1:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001107094.1	Gene:	sgk2a / 570956	ZFINID:	ZDB-GENE-030131-9632	Length:	361	Species:	Danio rerio

Alignment Length:	344	Identity:	137/344 - (39%)
Similarity:	193/344 - (56%)	Gaps:	14/344 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   357 PHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKK 421
            ||       .:..||:|:.|||||:|||||||:.:...:.||||||:|.||::..:.:..|.|:.
Zfish    23 PH-------AKPTDFDFLAVIGKGTFGKVLLAKLKADGKFYAVKVLQKKVILKKKEQKNIMAERN 80

  Fly   422 ILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFL 486
            :|..|.:.||||.:|..|||.::|:||::|..||:|.||:|:...|.|..|.||..|||.|:.:|
Zfish    81 VLLKSLKHPFLVGLHYSFQTSEKLYFVLDYVNGGELFYHLQRERCFSEPRARFYTAEVASAIGYL 145

  Fly   487 HERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAA 551
            |..:|:|||||.:|||||.:|||.|.||||.|||:....||.||||||.|:|||::..:||....
Zfish   146 HSLNIVYRDLKPENILLDYQGHVVLTDFGLCKEGIEPEGTTTTFCGTPEYLAPEVLRKEPYDRTV 210

  Fly   552 DWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGA- 615
            |||..|.:|.|.:....||...|.:.::..|..|....|...|..|..::...|.|..:.|.||
Zfish   211 DWWCLGAVLHEMLYSLPPFYSRDVSEMYDAILHKPLHLPPGKSESACLLLYGLLQKDQHRRTGAI 275

  Fly   616 GRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKE----KTDLTPTDKL 676
            ..:.  ||..|.||..::||......:.||..|.::...|:.:.|..||:|    ....||....
Zfish   276 ADFL--EIKNHVFFAPINWDDLYHKRITPPYNPNVRGPADLQHIDPEFTREMVPHSVGRTPEPTP 338

  Fly   677 FMMNLDQNDFIGFSFMNPE 695
            .:.....|.|.|||:::.|
Zfish   339 SLATSSSNAFTGFSYISGE 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_1	72..124	CDD:278556
		C1_1	137..189	CDD:278556
		C2_PKC_alpha_gamma	194..324	CDD:175992
		S_TKc	371..629	CDD:214567	114/258 (44%)
		STKc_PKC	375..692	CDD:270722	131/321 (41%)
sgk2a	NP_001107094.1	S_TKc	30..287	CDD:214567	114/258 (44%)
sgk2a	NP_001107094.1	STKc_SGK2	34..355	CDD:270754	131/322 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010