Protein Alignment inaC and PRKX

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_005035.1
• Gene: PRKX / 5613
• HGNCID: 9441
• Length: 358
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 103/291 - (35%)
• Similarity: 165/291 - (56%)
• Gaps: 4/291 - (1%)

  Fly   370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVS 434
            ||:.:..:|.|:||:|.|.:.:.....:|:||:....:|:....:...|||.:|..... |||:.
Human    48 DFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKEVSH-PFLIR 111

  Fly   435 MHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLD 499
            :...:.....|:.:|||..||:|..:::..|||..:..:||:.|:..|:.:||.::|:|||||.:
Human   112 LFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEIICAIEYLHSKEIVYRDLKPE 176

  Fly   500 NILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFM 564
            |||||.:||:||.|||.:|:.|   ..|.|.||||.|:|||::....:..|.|||:.|:|:||.:
Human   177 NILLDRDGHIKLTDFGFAKKLV---DRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEML 238

  Fly   565 AGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFF 629
            :|..||..|:...:::.|...|..||:|......|:|...|......|||..:....::..|.:|
Human   239 SGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKKLLVVDRTRRLGNMKNGANDVKHHRWF 303

  Fly   630 RNVDWDKAEACEMEPPIKPMIKHRKDISNFD 660
            |:|||:.....:::|||.|.|....|.|||:
Human   304 RSVDWEAVPQRKLKPPIVPKIAGDGDTSNFE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992
		STKc_PKC	375..692	CDD:270722	101/286 (35%)
PRKX	NP_005035.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		STKc_PRKX_like	47..338	CDD:270763	103/291 (35%)