Protein Alignment inaC and PRKCZ

DIOPT Version :9

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_016857278.1
• Gene: PRKCZ / 5590
• HGNCID: 9412
• Length: 603
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 188/637 - (29%)
• Similarity: 268/637 - (42%)
• Gaps: 218/637 - (34%)

  Fly    16 PSVPSAAPGAKAPAAGAGKGPGNLLEITGEANIVNYMKNRLRKGAMKRKGLEMVNGHRFGVRFFK 80
            ||.|. .||...|               ||.      |:..|:||.:.:.|...|||.|..:.|.
Human    97 PSTPE-QPGLPCP---------------GED------KSIYRRGARRWRKLYRANGHLFQAKRFN 139

  Fly    81 NPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADCAKVKHGWISTTYT 145
            ...|||.|.:.|||..:||::|..|:..:|::|                       ||.:..|
Human   140 RRAYCGQCSERIWGLARQGYRCINCKLLVHKRC-----------------------HGLVPLT-- 179

  Fly   146 TPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMCGADISEVRGKLLLYVELKGNNLKV 210
                                    |..::........||                         |
Human   180 ------------------------CRKHMDSVMPSQEPP-------------------------V 195

  Fly   211 DIK-EAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKR 274
            |.| |.|:|...:|:|.:  ||:       |.|.....|...::|.||
Human   196 DDKNEDADLPSEETDGIA--YIS-------SSRKHDSIKDDSEDLKPV----------------- 234

  Fly   275 LLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEV 339
                                           :||
Human   235 -------------------------------IDG------------------------------- 237

  Fly   340 RHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRK 404
                       ||...:...:..:      ||:.::|||:||:.||||...:..|::||:||::|
Human   238 -----------MDGIKISQGLGLQ------DFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKK 285

  Fly   405 DVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMD--------RLFFVMEYCKGGDLMYHM 461
            :::...:|::....||.:...:...||||.:||||||..        |||.|:||..|||||:||
Human   286 ELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRLFLVIEYVNGGDLMFHM 350

  Fly   462 QQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQT 526
            |:..:..|..|.|||.|:.|||.|||||.||||||||||:|||.:||:||.|:|:.|||:....|
Human   351 QRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDT 415

  Fly   527 TRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPF-------EGDDETTVFRNIKD 584
            |.||||||||:||||:..:.|..:.|||:.|||:||.|||::||       :.:.|..:|:.|.:
Human   416 TSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILE 480

  Fly   585 KKAVFPKHFSVEAMDIITSFLTKKPNNRLGA-GRYARQEITTHPFFRNVDWD 635
            |....|:..||:|..::..||.|.|..|||. .:....:|.:|.|||::|||
Human   481 KPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWD 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_1	72..124	CDD:278556	16/51 (31%)
		C1_1	137..189	CDD:278556	6/51 (12%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	18/130 (14%)
		S_TKc	371..629	CDD:214567	124/273 (45%)
		STKc_PKC	375..692	CDD:270722	129/277 (47%)
PRKCZ	XP_016857278.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614710at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850