Protein Alignment inaC and PKD

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_001262705.1
• Gene: PKD / 42203
• FlyBaseID: FBgn0038603
• Length: 906
• Species: Drosophila melanogaster
• Alignment Length: 838
• Identity: 187/838 - (22%)
• Similarity: 305/838 - (36%)
• Gaps: 251/838 - (29%)

  Fly    39 LLEITGEANIVNYMKNRLRKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCE 103
            |:||...|:.:.|..:.          :..:..|...|..:|.||:|..|.:.::|..:||.:|:
  Fly    82 LVEIVLTASPILYPTSE----------MPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCD 136

  Fly   104 ECRFNIHQKCCKFVVFKC----------------------------------------------P 122
            .|..|.|::|...:...|                                              |
  Fly   137 GCGQNYHKRCVVKIPNNCNRSNDATSRRSFTLQAPRSPSGSSQQSLVSTEDSTGRNDSSSSLNIP 201

  Fly   123 GKDTDFDAD-------CAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQE 180
            |:.....:.       ..::.|.::..||..||.|..|..||.|:..||::|.:|..|.|..|.:
  Fly   202 GRHQRTHSSGSRNGLMVLRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMD 266

  Fly   181 TVPPMC------------------------------GADISEVRGKLLLYVELKGNNLKVDIKEA 215
            .||..|                              |.|.||. ||           .|..:...
  Fly   267 KVPHDCTGEAQLSQLQIQAGAKERDNFFREEFDDSDGDDGSEY-GK-----------YKSAMSSG 319

  Fly   216 ANLI---PMD-----TNGFSDPYIAVQ--MHPDRS---GRTKKKTKTIQK-------NLNPVFNE 260
            .||:   |.:     ||..:.|...|.  :..|.|   |.|.|.:...|.       :.:|..|.
  Fly   320 VNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANI 384

  Fly   261 TFTFELQ----PQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYK----FLSQVE 317
            .....:|    .:.|..:.|.|.|....||.:..:..:.:.|:.          |    |:|: :
  Fly   385 PLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDS----------KTITLFVSE-Q 438

  Fly   318 GEHYN--IPCVDAFNDIARLRD---------EVR---------HDRRPNEKRRMDNKDMPHN--- 359
            |..|:  :|..:..:..:.|.|         |:|         .|.:...|.....:..|.:
  Fly   439 GSKYHKELPLAELLSIESHLGDPRPECNYCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGI 503

  Fly   360 -----MSKRDMIRAADFNFV-----------------------KVIGKGSFGKVLLAERRGTDEL 396
                 .|....||.|..:..                       :|:|.|.||.|.....:.|...
  Fly   504 GSDIAKSWETSIRQAFMHVTNTQCCESEEQVQDMGQLYQIFPDEVLGSGQFGVVYGGVHKKTQRE 568

  Fly   397 YAVKVLRKDVIIQTDDMELPMNEKKIL---ALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDL- 457
            .|:||:.|.......:.:| .||..||   :..|    :|::...|:|.:|:|.|||..||..|
  Fly   569 VAIKVIDKLRFPTKQEAQL-KNEVAILQNISHCG----VVNLERMFETPERIFVVMEKLKGDMLE 628

  Fly   458 MYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEG---HVKLVDFGLSKE 519
            |......||..|.|..|...::.|||.:||.::|::.|||.:|:||..:.   .|||.|||.::.
  Fly   629 MILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARI 693

  Fly   520 GVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKD 584
             :.|:...|:..|||.|:|||::....|:.:.|.||.||:::..::|..||  ::|..:...|::
  Fly   694 -IGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPF--NEEEDINDQIQN 755

  Fly   585 KKAVFP----KHFSVEAMDIITSFLTKKPNNR---------------------------LGAGRY 618
            ...::|    |..|..|:|:|.:.|..|...|                           :|||||
  Fly   756 AAFMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQDKQTYRDLRNLEAQVGAGRY 820

  Fly   619 ARQEITTHPFFRNVDWDKAEACEMEPPIKP--MIKHRKDISNFDDAFTKEKTDLTPTD 674
            ...|..      ::.||.|.  :| |..:|  :::...::.:.....|.|....:|.|
  Fly   821 LTHEAD------DLRWDCAG--DMXPGCEPEAILESTTELISCSANTTTESYRRSPAD 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	16/97 (16%)
		C1	137..190	CDD:412127	21/82 (26%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	31/159 (19%)
		STKc_PKC	375..692	CDD:270722	97/340 (29%)
PKD	NP_001262705.1	C1_PKD_rpt1	102..157	CDD:410345	16/54 (30%)
		C1_PKD_rpt2	222..275	CDD:410346	20/52 (38%)
		PH_PKD	396..522	CDD:269945	24/136 (18%)
		STKc_PKD	539..798	CDD:270984	81/266 (30%)