DRSC/TRiP Functional Genomics Resources

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Protein Alignment inaC and dop

DIOPT Version :10

Sequence 1:NP_476863.1 Gene:inaC / 36897 FlyBaseID:FBgn0004784 Length:700 Species:Drosophila melanogaster
Sequence 2:NP_648778.1 Gene:dop / 39686 FlyBaseID:FBgn0267390 Length:2139 Species:Drosophila melanogaster


Alignment Length:355 Identity:118/355 - (33%)
Similarity:176/355 - (49%) Gaps:43/355 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   370 DFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVS 434
            ||:.||:|..|::|.|.|.:.:.|.:.:|:|.:.|:.:|..:.:|....|:.||:.:.. ||:||
  Fly   834 DFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADN-PFVVS 897

  Fly   435 MHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLD 499
            |:..|:|...|..||||.:|||....::..|.....:|.||..|..:|:.:||...|::||||.|
  Fly   898 MYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPD 962

  Fly   500 NILLDGEGHVKLVDFGLSKEGVTERQT----------TRTFC-----GTPNYMAPEIVSYDPYSI 549
            |:|:...||:||.||||||.|:....|          ||.|.     |||.|:|||::....|..
  Fly   963 NLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGK 1027

  Fly   550 AADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKH----FSVEAMDIITSFLTKKPN 610
            ..||||.|::|:||:.|..||.|:....:|.:..:....:|..    ...||.|||:..|.:.|.
  Fly  1028 PVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPR 1092

  Fly   611 NRLGAGRYARQEITTHPFFRNVDWD-----KAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDL 670
            :|||. :....|:..|.:|..:||:     |||       ..|.:.|..|.|.||....:...||
  Fly  1093 DRLGT-QSGALEMKEHEYFLGMDWNSLLRQKAE-------FVPQLSHDDDTSYFDTRMDRYNHDL 1149

  Fly   671 TPTDKLFMMNLDQND----FIGFSFMNPEF 696
            ...|      .|..|    |..|:...|::
  Fly  1150 GGED------TDDTDDTPVFGSFNSYTPQY 1173

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
inaCNP_476863.1 C1_cPKC_nPKC_rpt1 71..123 CDD:410342
C1 137..190 CDD:412127
C2_PKC_alpha_gamma 194..324 CDD:175992
STKc_PKC 375..692 CDD:270722 114/344 (33%)
dopNP_648778.1 DUF1908 344..702 CDD:462637
STKc_MAST 834..1115 CDD:270760 99/282 (35%)
PDZ_MAST 1502..1594 CDD:467189
Blue background indicates that the domain is not in the aligned region.

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