DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaC and Pkn3

DIOPT Version :9

Sequence 1:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_006233834.1	Gene:	Pkn3 / 296619	RGDID:	1305921	Length:	883	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	138/341 - (40%)
Similarity:	195/341 - (57%)	Gaps:	4/341 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 MSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILA 424
            :|.|:..:..||..:.|:|:|.||||||.:.:||.:.||:|.|:|..::..|:::....||:||.
  Rat   542 LSTRNPPQLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILE 606

  Fly   425 LSGRP--PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLH 487
            ..||.  |||:|:.:|.||.....||.|:..|||||..:.: ..|.|..|.||...|.:.|.|||
  Rat   607 TVGRTGHPFLLSLLACIQTSSHACFVTEFLPGGDLMMQIHE-DVFPEPQACFYLACVVLGLQFLH 670

  Fly   488 ERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAAD 552
            |:.||||||||||:|||.:|.:|:.||||.|||:.....|.||||||.::|||:::.:.|:.|.|
  Rat   671 EKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVD 735

  Fly   553 WWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGR 617
            ||..||||:|.:.|:.||.||.|..||..|.:.....|...|.:.:::|...|.|.|..|||||.
  Rat   736 WWGLGVLLYEMLVGECPFPGDTEDEVFECIVNADVPCPHFLSAQGLELIQKLLQKSPEKRLGAGE 800

  Fly   618 YARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLT-PTDKLFMMNL 681
            ...:||...||||..:|....|..::||..|.:....|:..|:..||.....|| |..:..:...
  Rat   801 RDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVPRRSLSAR 865

  Fly   682 DQNDFIGFSFMNPEFI 697
            .|..|..|.|::..|:
  Rat   866 QQAAFRDFDFVSKRFL 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_1	72..124	CDD:278556
		C1_1	137..189	CDD:278556
		C2_PKC_alpha_gamma	194..324	CDD:175992
		S_TKc	371..629	CDD:214567	115/259 (44%)
		STKc_PKC	375..692	CDD:270722	132/319 (41%)
Pkn3	XP_006233834.1	HR1_PKN_1	14..79	CDD:212012
		HR1	95..168	CDD:294066
		HR1	168..>226	CDD:294066
		C2	326..413	CDD:301316
		PTZ00263	549..873	CDD:140289	133/324 (41%)
		PKc_like	553..877	CDD:304357	134/324 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930