DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment inaC and Pkn3

DIOPT Version :9

Sequence 1:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_030107417.1	Gene:	Pkn3 / 263803	MGIID:	2388285	Length:	914	Species:	Mus musculus

Alignment Length:	341	Identity:	140/341 - (41%)
Similarity:	195/341 - (57%)	Gaps:	4/341 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   360 MSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILA 424
            :|.|...|..||..:.|:|:|.||||||.:.:||.:.||:|.|:|..::..|:::....||:||.
Mouse   573 LSTRKPPRLQDFRCLAVLGRGHFGKVLLVQYKGTGKYYAIKALKKQEVLGRDEIDSLYCEKRILE 637

  Fly   425 LSGRP--PFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLH 487
            ..||.  |||:|:.:|.||.....||.|:..|||||..:.: ..|.|..|.||...|.:.|.|||
Mouse   638 TVGRTGHPFLLSLLACLQTSSHACFVTEFLPGGDLMAQIHE-DVFPEPQACFYLACVVLGLQFLH 701

  Fly   488 ERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAAD 552
            |:.||||||||||:|||.:|.:|:.||||.|||:.....|.||||||.::|||:::.:.|:.|.|
Mouse   702 EKRIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVD 766

  Fly   553 WWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGR 617
            ||..||||:|.:.|:.||.||.|..||..|.......|...||:.:::|...|.|.|..|||||.
Mouse   767 WWGLGVLLYEMLVGECPFPGDTEEEVFECIVSADVPCPHFLSVQGLELIQKLLQKSPEKRLGAGE 831

  Fly   618 YARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLT-PTDKLFMMNL 681
            ...:||...||||..:|....|..::||..|.:....|:..|:..||.....|| |..:..:...
Mouse   832 RDAEEIKVQPFFRTTNWQALLARTVQPPFVPTLCGPADLRYFEGEFTSLPPTLTPPVSQSSLTAR 896

  Fly   682 DQNDFIGFSFMNPEFI 697
            .|..|..|.|::.:|:
Mouse   897 QQAAFRDFDFVSEQFL 912

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_1	72..124	CDD:278556
		C1_1	137..189	CDD:278556
		C2_PKC_alpha_gamma	194..324	CDD:175992
		S_TKc	371..629	CDD:214567	116/259 (45%)
		STKc_PKC	375..692	CDD:270722	133/319 (42%)
Pkn3	XP_030107417.1	HR1_PKN_1	23..88	CDD:212012
		HR1	103..176	CDD:381797
		HR1	203..>257	CDD:381797
		C2	357..444	CDD:387358
		STKc_PKN	584..909	CDD:270741	135/325 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930