Protein Alignment inaC and Prkcg

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_036760.1
• Gene: Prkcg / 24681
• RGDID: 3397
• Length: 697
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 345/687 - (50%)
• Similarity: 456/687 - (66%)
• Gaps: 28/687 - (4%)

  Fly    32 AGKGPGNLLEITGEANIVNYMKNRLRKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFG 96
            ||.|||......|...:.      .||||:::|.:..|..|:|..||||.||:|.||.|||||.|
  Rat     2 AGLGPGGGDSEGGPRPLF------CRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG 60

  Fly    97 KQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADCAKVKHGWISTTYTTPTFCDECGLLLHGVA 161
            |||.||:.|.|.:|::|.:||.|:|||.......|..:.||.:...:|::|||||.||.||:|:.
  Rat    61 KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSLLYGLV 125

  Fly   162 HQGVKCENCNLNVHHACQETVPPMCGADISEVRGKLLLYVEL-KGNNLKVDIKEAANLIPMDTNG 225
            |||:||..|.:|||..|..:||.:||.|.:|.||:|.|.:.. ..:.:.:.:.||.||||||.||
  Rat   126 HQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEARNLIPMDPNG 190

  Fly   226 FSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDF 290
            .||||:.:::.||....||:||||::..||||:||||.|.|:|.|.::||.:|||||||||||||
  Rat   191 LSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTSRNDF 255

  Fly   291 MGSFSFSLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFN-DIARLRDEVRHDRRPNEKRRMDNK 354
            ||:.||.:.||.|.|||||||.|:|.|||:||:|..||.| .:.:..:...:.....|:.||...
  Rat   256 MGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQKFEACNYPLELYERVRMGPS 320

  Fly   355 DMP-------HNMSKR-------DMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKD 405
            ..|       ...|||       ..:..:||:|:.|:||||||||:||||||:|||||:|:|:||
  Rat   321 SSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLAERRGSDELYAIKILKKD 385

  Fly   406 VIIQTDDMELPMNEKKILAL-----SGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYG 465
            ||:|.||::..:.||::|||     .|||.||..:||.|||.|||:|||||..|||||||:||.|
  Rat   386 VIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQLHSTFQTPDRLYFVMEYVTGGDLMYHIQQLG 450

  Fly   466 RFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTF 530
            :|||..|.|||.|:||.|||||.:.||||||||||::||.|||:|:.|||:.||.|....|||||
  Rat   451 KFKEPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTF 515

  Fly   531 CGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSV 595
            ||||:|:||||::|.||..:.|||||||||:|.:|||.||:|:||..:|:.|.::...:||..|.
  Rat   516 CGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSR 580

  Fly   596 EAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFD 660
            ||:.|...||||.|..|||:|......|..|.|||.:||::.|..|:.||.:|....|.. .|||
  Rat   581 EAVAICKGFLTKHPGKRLGSGPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSG-ENFD 644

  Fly   661 DAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEFI 697
            ..||:....|||.|:|.:.::||.||.||:::||:|:
  Rat   645 KFFTRAAPALTPPDRLVLASIDQADFQGFTYVNPDFV 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	30/51 (59%)
		C1	137..190	CDD:412127	26/52 (50%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	74/130 (57%)
		STKc_PKC	375..692	CDD:270722	180/321 (56%)
Prkcg	NP_036760.1	C1_cPKC_rpt1	34..91	CDD:410383	32/56 (57%)
		C1_cPKC_rpt2	101..154	CDD:410386	26/52 (50%)
		C2_PKC_alpha_gamma	158..289	CDD:175992	74/130 (57%)
		STKc_cPKC	354..677	CDD:270739	180/323 (56%)