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Protein Alignment inaC and AKT2

DIOPT Version :9

Sequence 1:	NP_476863.1	Gene:	inaC / 36897	FlyBaseID:	FBgn0004784	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001617.1	Gene:	AKT2 / 208	HGNCID:	392	Length:	481	Species:	Homo sapiens

Alignment Length:	365	Identity:	146/365 - (40%)
Similarity:	215/365 - (58%)	Gaps:	18/365 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   343 RRPNEKRRMDNK-----------DMPHNMSK-RDMIRAADFNFVKVIGKGSFGKVLLAERRGTDE 395
            |.|.|. .||.|           :|...:|| |..:...||:::|::|||:||||:|...:.|..
Human   113 RAPGED-PMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGR 176

  Fly   396 LYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYH 460
            .||:|:|||:|||..|::...:.|.::|. :.|.|||.::...|||.|||.|||||..||:|.:|
Human   177 YYAMKILRKEVIIAKDEVAHTVTESRVLQ-NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH 240

  Fly   461 MQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQ 525
            :.:...|.|..|.||..|:..||.:||.||::|||:||:|::||.:||:|:.||||.|||:::..
Human   241 LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGA 305

  Fly   526 TTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFP 590
            |.:||||||.|:|||::..:.|..|.|||..||:::|.|.|:.||...|...:|..|..::..||
Human   306 TMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFP 370

  Fly   591 KHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKD 655
            :..|.||..::...|.|.|..|||.|....:|:..|.||.:::|......::.||.||.:....|
Human   371 RTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVD 435

  Fly   656 ISNFDDAFTKEKTDLTPTDK---LFMMNLDQ-NDFIGFSF 691
            ...|||.||.:...:||.|:   |.::.||| ..|..||:
Human   436 TRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSY 475

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.