Protein Alignment inaC and Prkcd

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_579841.2
• Gene: Prkcd / 170538
• RGDID: 67383
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 654
• Identity: 235/654 - (35%)
• Similarity: 329/654 - (50%)
• Gaps: 143/654 - (21%)

  Fly    57 RKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKC 121
            |:||:|:..:..:..|.|...||..||:|..||:|:||..|||::|.:|...||:||...::.:|
  Rat   144 RRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRC 208

  Fly   122 PG-----KDTDFDADCAKV--KHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQ 179
            .|     :||.|..:...:  .|.:....|.:|||||.||.||.|:..||:|||:|.:||||.|:
  Rat   209 TGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCR 273

  Fly   180 ETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTK 244
            |.|..:||     :..|||              .||.|.:                       |:
  Rat   274 EKVANLCG-----INQKLL--------------AEALNQV-----------------------TQ 296

  Fly   245 KKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGW 309
            |.::      .|...||                             :|.:            .|:
  Rat   297 KASR------KPETPET-----------------------------VGIY------------QGF 314

  Fly   310 YKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKRRMDNKDMPHNMSKRDMI-------R 367
            .|                                    |..:...|:|.|......|       |
  Rat   315 EK------------------------------------KTAVSGNDIPDNNGTYGKIWEGSNRCR 343

  Fly   368 AADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFL 432
            ..:|.|.||:||||||||||||.:|.:..:|:|.|:|||::..||:|..|.||::|||:...|||
  Rat   344 LENFTFQKVLGKGSFGKVLLAELKGKERYFAIKYLKKDVVLIDDDVECTMVEKRVLALAWENPFL 408

  Fly   433 VSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLK 497
            ..:...|||.|.||||||:..|||||:|:|..|||:...|.|||.|:...|.|||.:.|||||||
  Rat   409 THLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHGKGIIYRDLK 473

  Fly   498 LDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFE 562
            |||::||.:||:|:.|||:.||.:.......||||||:|:||||:....||.:.|||||||||:|
  Rat   474 LDNVMLDKDGHIKIADFGMCKENIFGENRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYE 538

  Fly   563 FMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHP 627
            .:.||:||.||||..:|.:|:.....:|:..:.|:.||:.....:.|..|||    ....|..||
  Rat   539 MLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPAKRLG----VTGNIRLHP 599

  Fly   628 FFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFM 692
            ||:.::|:..|..::|||.||.:|...|.||||..|..||..|:.:||..:.::||..|.||||:
  Rat   600 FFKTINWNLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQTAFKGFSFV 664

  Fly   693 NPEF 696
            ||::
  Rat   665 NPKY 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	22/51 (43%)
		C1	137..190	CDD:412127	27/52 (52%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	14/129 (11%)
		STKc_PKC	375..692	CDD:270722	153/316 (48%)
Prkcd	NP_579841.2	C1_nPKC_theta-like_rpt1	152..212	CDD:410384	23/59 (39%)
		C1_nPKC_theta-like_rpt2	231..280	CDD:410387	25/48 (52%)
		Protein Kinases, catalytic domain	351..666	CDD:473864	154/318 (48%)