Protein Alignment inaC and Pkc98E

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_061497978.1
• Gene: Pkc98E / 1273220
• VectorBaseID: AGAMI1_006338
• Length: 767
• Species: Anopheles gambiae
• Alignment Length: 687
• Identity: 268/687 - (39%)
• Similarity: 369/687 - (53%)
• Gaps: 128/687 - (18%)

  Fly    54 NRLRKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVV 118
            || |:|||:|: :..||||:|...|.:.||:|.||::||||.||||:||:.|...:|::|...||
Mosquito   157 NR-RRGAMRRR-VHQVNGHKFMATFLRQPTFCSHCREFIWGLGKQGYQCQVCTCVVHKRCHSSVV 219

  Fly   119 FKCPGKDTD------------FDADCAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCN 171
            .|||.|..:            |:.:   :.|.:...::...||||.||.||:|:..||:|||.|:
Mosquito   220 TKCPKKKDEQTKPTPTEAAQRFNVN---MPHRFSVHSFKRLTFCDHCGSLLYGIIRQGLKCEVCS 281

  Fly   172 LNVHHACQETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANL-----IPMDTNGFSDPYI 231
            :|:|..|:..|...||                      ::.|:.|.|     |.||
Mosquito   282 MNIHRRCEGNVANNCG----------------------INTKQLAELLNEMGITMD--------- 315

  Fly   232 AVQMHPDRSGRTKKKTKTIQKNL----------NPVFNETFTFELQPQDRDKRLLIEVWDWDRTS 286
              :..|.||...:.:...:|.:|          |...|:|.:..|...:|.          |.||
Mosquito   316 --KTPPRRSKVGEVRCIKMQHSLLMLTYFSFICNQYSNQTTSDNLSMSERS----------DDTS 368

  Fly   287 RNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGE-----------------HYNIPCVDAFNDIAR 334
                      ||:.|..:         |..|||                 |.:.........:..
Mosquito   369 ----------SLDTLSTK---------SGAEGELGAHGGGGGGGGRGGAGHSSKAGGPTMGMLVN 414

  Fly   335 LRDEVRHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAV 399
            |..:...:.||          ||      ..:...||||:||:||||||||:|||::||||:||:
Mosquito   415 LGTDDDGNARP----------MP------GKVFLNDFNFIKVLGKGSFGKVMLAEKKGTDEVYAI 463

  Fly   400 KVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQY 464
            |||:||||:|.||::..|.||:||||:.:.|||.::||||||.|||||||||..|||||:.:|:.
Mosquito   464 KVLKKDVILQDDDVDCTMTEKRILALAAKHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQRA 528

  Fly   465 GRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRT 529
            .:|.|..|.|||.||.:||.|||...:|||||||||||||.|||.||.|||:.|||:|....|.|
Mosquito   529 RKFDEPRAAFYAAEVTLALQFLHRNGVIYRDLKLDNILLDAEGHCKLADFGMCKEGITGDNLTST 593

  Fly   530 FCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFS 594
            |||||:|:||||:....|..:.|||:.|||::|.||||.|||.|:|..:|..|.....::|...|
Mosquito   594 FCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILRDDVLYPVWLS 658

  Fly   595 VEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNF 659
            .||:.|:..|:||....|||. .....:|.:||||:::||:..|..::.||.:|.::..:|..||
Mosquito   659 REAVSILKGFMTKNAAKRLGC-TDGENQIRSHPFFKDMDWEALEQRKVRPPFRPRVRSARDALNF 722

  Fly   660 DDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEF 696
            |..||||...|||.....:..::|::|.||||.||||
Mosquito   723 DTEFTKEDPVLTPVPNDIIRCINQDEFAGFSFTNPEF 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	26/51 (51%)
		C1	137..190	CDD:412127	22/52 (42%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	27/161 (17%)
		STKc_PKC	375..692	CDD:270722	167/316 (53%)
Pkc98E	XP_061497978.1	None