Protein Alignment inaC and pkn2

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_004913783.1
• Gene: pkn2 / 100488854
• XenbaseID: XB-GENE-995298
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 192/554 - (34%)
• Similarity: 279/554 - (50%)
• Gaps: 87/554 - (15%)

  Fly   194 RGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGR--TKKKTKTI----QK 252
            |..:.||:|.:| .|..::.            |.:|.|..:....|..:  :|::.||.    |.
 Frog   457 RHGMCLYLEPQG-TLFAEVT------------FFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQM 508

  Fly   253 NLN------------PVFNETFTFELQ-------PQDRDKRLLIEVWDWDRTSRNDFMGSFSFSL 298
            |:|            |..|.:.|:..|       |....:.|.:........::.||
 Frog   509 NINIATWGRLVRRAIPTVNHSGTYSPQVAVPAAVPVVDPRNLELSPISESTVAKLDF-------- 565

  Fly   299 EELQKE-----PVDGWYKFLSQVEGEHY--NIPCVDA--------FNDIARLRDEVRHDR----- 343
             :|:.|     |.......|.|...||.  |:|..|.        .:.||:...||..:.
 Frog   566 -DLEPEAPPAPPRSSSLGDLYQPSAEHKAPNVPVPDTNYENSNNRISVIAKPTAEVTIEPEIPVS 629

  Fly   344 -------RPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKV 401
                   ..:|.||         :.:|......||:...|:|:|.||||||||.:.|:|::|:|.
 Frog   630 DMNYSTIEESEDRR---------IQQRFQFSLQDFHCCAVLGRGHFGKVLLAEYKSTNEMFAIKA 685

  Fly   402 LRKDVIIQTDDMELPMNEKKILAL--SGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQY 464
            |:|..|:..|:::..|.||:|...  |.|.||||::.:||||.|.:.|||||..|||||.|:..
 Frog   686 LKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACFQTKDHVCFVMEYAAGGDLMMHIHT- 749

  Fly   465 GRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRT 529
            ..|.|..|:|||..|.:.|.:|||..|:||||||||:|||.||.||:.||||.|||:.....|.|
 Frog   750 DVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGFGDRTST 814

  Fly   530 FCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFS 594
            |||||.::|||:::...|:.|.|||..|||::|.:.|::||.||||..||.:|.:.:..:|:..|
 Frog   815 FCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLS 879

  Fly   595 VEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNF 659
            .||:.|:...|.:.|..||||.....:::..|||||:.||:...|.:::||..|.||.|:|:|||
 Frog   880 TEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRHTDWNALLAKKVKPPFVPTIKGREDVSNF 944

  Fly   660 DDAFTKEKTDLT-PTDKLFMMNLDQNDFIGFSFM 692
            ||.||.|...|| |.:...:...:|..|..|.::
 Frog   945 DDEFTSEAPILTPPREPRILTEEEQEAFRDFDYI 978

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992	32/161 (20%)
		STKc_PKC	375..692	CDD:270722	148/319 (46%)
pkn2	XP_004913783.1	HR1_PKN_1	40..105	CDD:212012
		HR1	129..197	CDD:469609
		HR1	208..281	CDD:469609
		C2_PKN-like	390..471	CDD:176069	5/14 (36%)
		STKc_PKN	655..980	CDD:270741	149/325 (46%)