Protein Alignment inaC and lats1

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_017949762.1
• Gene: lats1 / 100145677
• XenbaseID: XB-GENE-959763
• Length: 1117
• Species: Xenopus tropicalis
• Alignment Length: 610
• Identity: 161/610 - (26%)
• Similarity: 255/610 - (41%)
• Gaps: 162/610 - (26%)

  Fly   219 IPMDTNGFSDPYIAVQ---------------------MHPDRSGRTKK--------------KTK 248
            ||:.:|.|::|..:.|                     ..|.:|.|..|              .|.
 Frog   449 IPVRSNSFNNPVASWQALSTNTQTSATTVTAVTPSPIQQPVKSIRVLKPELQTALAPTHPTWMTP 513

  Fly   249 TIQ---------KNLNPVFNETFTFELQPQDRDKRLLIE---VWDWD-RTSRNDFMGSFSFSLEE 300
            .:|         .|.:....|...::..|....|.||.:   |::.. ::|:.|..|..:.:.||
 Frog   514 NVQPGPFQEGVSHNTSAQLAEAPNYQGPPPPYPKHLLQQNTTVYEPGLKSSKEDAAGVSTCTQEE 578

  Fly   301 LQK--EPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVR---------------------HD 342
            ::|  ||..|   ...:.:.....:|......|..|...:::                     |.
 Frog   579 MEKNTEPTTG---ITEKKQITTSPVPVRRNKRDEERRESQIQSYSPQAFKFFMEQHVENILKSHH 640

  Fly   343 RRPNEKRRMDNKDMPHNMSK------RDMIRAADFNF---------------VKVIGKGSFGKVL 386
            :|.:.|::::|:.|...:|:      |.|:...:.|:               :|.:|.|:||:|.
 Frog   641 QRLHRKKQLENEMMRVGLSQEAQDQMRKMLCQKESNYIRLKRAKMEKSMFVKIKTLGIGAFGEVC 705

  Fly   387 LAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEY 451
            ||.:..|:.|||:|.|||..::..:.:.....|:.|||.:.. .::|.::..||..|.|:|||:|
 Frog   706 LARKTDTNALYAMKTLRKKDVLLRNQVAHVKAERDILAEADN-EWVVRLYYSFQDKDNLYFVMDY 769

  Fly   452 CKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGL 516
            ..|||:|..:.:.|.|.|.:|.||..|:..|:..:|:.|.|:||:|.||||:|.:||:||.||||
 Frog   770 IPGGDMMSLLIRMGVFPEDLARFYIAELTCAVESVHKMDFIHRDIKPDNILIDRDGHIKLTDFGL 834

  Fly   517 S------------KEGVTERQTTRTF-----------------------------C------GTP 534
            .            :.|...||.:..|                             |      |||
 Frog   835 CTGFRWTHDSKYYQSGDHLRQDSMDFSNEWGDPANCRCGDRLKPLEWRAARQHQRCLAHSLVGTP 899

  Fly   535 NYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDET-TVFRNIKDKKAV-FPKH--FSV 595
            ||:|||::....|:...||||.||:|:|.:.||.||...... |..:.||.:..: .|..  .|.
 Frog   900 NYIAPEVLLRTGYTQLCDWWSVGVILYEMLVGQPPFLAQSPVETQMKVIKWQTTLHIPAQAKLSP 964

  Fly   596 EAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFD 660
            ||.|:|.. |.:.|.:||  |:....||..||||:|:|: .::..:...|..|.|.|..|.||||
 Frog   965 EASDLIVK-LCRGPEDRL--GKNGVDEIKVHPFFKNIDF-SSDLRQQPAPYTPTITHPTDTSNFD 1025

  Fly   661 DAFTKEKTDLTPTDKLFMMNLDQND 685
                       |.|...:.|.:..|
 Frog  1026 -----------PVDPEKLWNDEDKD 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342
		C1	137..190	CDD:412127
		C2_PKC_alpha_gamma	194..324	CDD:175992	28/154 (18%)
		STKc_PKC	375..692	CDD:270722	121/362 (33%)
lats1	XP_017949762.1	UBA_LATS1	102..142	CDD:270580
		MobB_LATS1	614..689	CDD:439273	9/74 (12%)
		STKc_LATS1	688..1069	CDD:270775	121/368 (33%)