Protein Alignment inaC and prkcq

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_012813823.2
• Gene: prkcq / 100038268
• XenbaseID: XB-GENE-487643
• Length: 699
• Species: Xenopus tropicalis
• Alignment Length: 658
• Identity: 235/658 - (35%)
• Similarity: 351/658 - (53%)
• Gaps: 115/658 - (17%)

  Fly    57 RKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKC 121
            |:||||:..:..|..|.|...||..||:|..|.:|:||..|||:||.:|...||:||...|:.||
 Frog   142 RRGAMKQAKVHQVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKC 206

  Fly   122 PG-----KDTDFDADCAKV--KHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQ 179
            .|     |:|....:..|:  .|.:....|.:||||:.||.||.|:|.||:||..||:||||.|.
 Frog   207 TGSAVNSKETVLHKERFKIDMPHRFKVNNYRSPTFCEHCGTLLWGLARQGLKCAECNMNVHHKCA 271

  Fly   180 ETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTK 244
            ..|..:||     |..||:                |..|..::|.              :..|.:
 Frog   272 VKVANLCG-----VNQKLM----------------AEALAMIETT--------------QQDRRQ 301

  Fly   245 KKTKTIQK----NLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMG-SFSFSLE--ELQ 302
            :.::.|.:    |:.|..|          .:|:.:::.:       :.:..| |:...:|  ::|
 Frog   302 RDSEFIYREGPVNVGPTTN----------TQDQPIVLSI-------KKESQGISWESPIESIKVQ 349

  Fly   303 KEPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKRRMDNKDMPHNMSKRDMIR 367
            :.|                                       |..:.:::..      |.:..:.
 Frog   350 ESP---------------------------------------PEPELKIEQS------SCQIKVT 369

  Fly   368 AADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFL 432
            .:||...|::||||||||.|||.:.|::.:|:|||:|||::..||:|..|.||::|:|:...|||
 Frog   370 FSDFVLHKMLGKGSFGKVFLAELKRTNQFFAIKVLKKDVVLMDDDVECTMVEKRVLSLAWEHPFL 434

  Fly   433 VSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLK 497
            ..::..|||.:.|||||||..|||||:|:|...:|....|.|||.|:...|.|||.:.::|||||
 Frog   435 THLYCTFQTKEHLFFVMEYLNGGDLMFHIQSCHKFDLPRATFYAAEIVCGLQFLHSKGVVYRDLK 499

  Fly   498 LDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFE 562
            |||||||.|||:|:.|||:.||.:.....|.||||||:|:||||:....|:.:.|||||||||:|
 Frog   500 LDNILLDMEGHIKIADFGMCKESMLGDAKTSTFCGTPDYIAPEILLGQKYNYSVDWWSFGVLLYE 564

  Fly   563 FMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHP 627
            .:.||:||.|.||..:|::|:....::|:..|:||.||:.....::|..|||    .:.:|..|.
 Frog   565 MLIGQSPFHGIDEEELFQSIRMDNPMYPRFLSMEAKDILIMLFVREPERRLG----VKGDIRQHC 625

  Fly   628 FFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFM 692
            ||:::||.:.|..|:|||.||.:|...|.||||..|..||..|:.:::..:.::|||.|..|||:
 Frog   626 FFQHIDWGRLENREIEPPFKPKVKSADDWSNFDKEFLNEKPRLSSSERTLINSMDQNMFNNFSFV 690

  Fly   693 NPEFITII 700
            ||:...|:
 Frog   691 NPKMEAIV 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	24/51 (47%)
		C1	137..190	CDD:412127	26/52 (50%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	16/136 (12%)
		STKc_PKC	375..692	CDD:270722	150/316 (47%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384	26/59 (44%)
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387	24/48 (50%)
		STKc_nPKC_theta	367..697	CDD:270770	155/333 (47%)