Protein Alignment inaC and prkcba

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_957323.1
• Gene: prkcba / 100006675
• ZFINID: ZDB-GENE-040426-1354
• Length: 668
• Species: Danio rerio
• Alignment Length: 652
• Identity: 331/652 - (50%)
• Similarity: 455/652 - (69%)
• Gaps: 13/652 - (1%)

  Fly    57 RKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKC 121
            |:||:::|.:..|..|:|..||||.||:|.||.|||||||||||||:.|.|.:|::|.:||.|.|
Zfish    18 RQGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVHFSC 82

  Fly   122 PGKDTDFDADCAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMC 186
            ||.|....:|..:..|.:...|||:|||||.||.||:|:.|||::|.||.:|:|..|.:.||.:|
Zfish    83 PGSDKGPASDDPRKYHSFKVHTYTSPTFCDHCGSLLYGLIHQGMRCLNCLMNIHKRCFKHVPSLC 147

  Fly   187 GADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQ 251
            |.|.:|.||:|.....:.||.|.|.:|||.||:|||.:|.||||:.:::.||....:|:|||||:
Zfish   148 GTDHTEKRGRLHFSASITGNVLSVSVKEARNLVPMDPSGLSDPYVKLKLIPDPKSESKQKTKTIK 212

  Fly   252 KNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQV 316
            ..||||:||.|||.|:..|:|:||.:|||||||.:|||:|||.||.:.||..:.||||:|.|:..
Zfish   213 GCLNPVWNEDFTFALKDTDKDRRLYVEVWDWDRGTRNDYMGSMSFGISELMNQSVDGWFKILACE 277

  Fly   317 EGEHYNIPCV----DAFNDIARLRDEVRHDRRPN-----EKRRMDNKDMPHNMSKRDMIRAADFN 372
            ||..:|:|..    :...::::..:..:.....|     .|..:...|...|   :|.::.||||
Zfish   278 EGVFFNVPVYVDEEEGNKELSKRFERAKIGPGTNNTDGASKNDLSKYDANGN---QDRMKLADFN 339

  Fly   373 FVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHS 437
            |:.|:||||||||:||||:|:|||||||:|:|||:||.||:|..|.||::|||||:||||..:||
Zfish   340 FIMVLGKGSFGKVMLAERKGSDELYAVKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTHLHS 404

  Fly   438 CFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNIL 502
            ||||||||:|||||..|||||:.:||.|:|||.:|:|||.|:||.|||||.:.||||||||||::
Zfish   405 CFQTMDRLYFVMEYISGGDLMFQIQQTGKFKEPLAVFYAGEIAIGLFFLHSKGIIYRDLKLDNVM 469

  Fly   503 LDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ 567
            ||.|||:|:.|||:.||.:.::.||:||||||:|:||||::|.||..:.|||::||||:|.:|||
Zfish   470 LDSEGHIKIADFGMCKENMFDKDTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQ 534

  Fly   568 APFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNV 632
            .||:|:||..:|::|.:....:||..|.||:.|....:||.|..|||.|....::|..|.|||.|
Zfish   535 PPFDGEDEDELFQSIMEHHVSYPKSMSKEAVAICKGLMTKHPGKRLGCGLEGERDIKEHAFFRFV 599

  Fly   633 DWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEFI 697
            ||::.:..|::||.||....| |..|||..||:....|||.|...:.||||.:|.|||::|.:|.
Zfish   600 DWERLQNKEVQPPYKPKSCGR-DAGNFDLFFTRHPPILTPPDLEVIQNLDQEEFRGFSYVNTKFA 663

  Fly   698 TI 699
            ::
Zfish   664 SM 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	32/51 (63%)
		C1	137..190	CDD:412127	27/52 (52%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	68/129 (53%)
		STKc_PKC	375..692	CDD:270722	180/316 (57%)
prkcba	NP_957323.1	C1_cPKC_rpt1	31..88	CDD:410383	35/56 (63%)
		C1_cPKC_rpt2	98..151	CDD:410386	27/52 (52%)
		C2_PKC_alpha_gamma	155..285	CDD:175992	68/129 (53%)
		Protein Kinases, catalytic domain	337..659	CDD:473864	184/322 (57%)