Protein Alignment inaC and prkcg

DIOPT Version :10

• Sequence 1: NP_476863.1
• Gene: inaC / 36897
• FlyBaseID: FBgn0004784
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_001921715.1
• Gene: prkcg / 100003514
• ZFINID: ZDB-GENE-090206-1
• Length: 695
• Species: Danio rerio
• Alignment Length: 702
• Identity: 340/702 - (48%)
• Similarity: 463/702 - (65%)
• Gaps: 32/702 - (4%)

  Fly    11 ATVLPPSVPSAAPGA-KAPAAGAGKGPGNLLEITGEANIVNYMKNRL----RKGAMKRKGLEMVN 70
            :|.:.|| ||.:|.| .:|:..:...|..|..           ..||    ||||:|.|.:..|.
Zfish     2 STPVSPS-PSLSPLALSSPSPSSSPLPSPLSP-----------PPRLPVFQRKGALKHKRVIEVK 54

  Fly    71 GHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADCAKV 135
            .|:|..||||.||:|.||.|||||.|||||||:.|.|.:|::|.:||.|.|||..|....:..|.
Zfish    55 DHQFTARFFKQPTFCSHCTDFIWGIGKQGFQCQVCSFVVHKRCHEFVTFTCPGAITAPKPEDLKS 119

  Fly   136 KHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMCGADISEVRGKLLLY 200
            ||.:...||::|||||.||.||:|:.|||:||..|::|||..|:.:||.:||.|.:|.||::.|.
Zfish   120 KHKFKVHTYSSPTFCDHCGSLLYGLIHQGMKCGCCDMNVHKRCESSVPSLCGQDHTEKRGRIRLT 184

  Fly   201 VELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFE 265
            |..:..::.:.:.||.||||||.||.||||:.:::.||....:|:|||||:..|||::||:|||.
Zfish   185 VRGEKEDIYITVHEALNLIPMDPNGLSDPYVKLKLIPDPKSHSKQKTKTIRSTLNPIWNESFTFS 249

  Fly   266 LQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFN 330
            ::.:..|:||.:|||||||||||||||:.||.:.|:.:..|.||:|.|:|.|||:||||..|.
Zfish   250 VRGRQWDRRLSVEVWDWDRTSRNDFMGALSFGVSEIFRRSVSGWFKLLNQDEGEYYNIPVPDP-- 312

  Fly   331 DIARLRDEVRHDRRPNEKRRMDN---KDMPHNMSK--------RDMIRAADFNFVKVIGKGSFGK 384
            |: ::.:|:.....|.....:..   ...|..:|.        :..|...||||:.|:|||||||
Zfish   313 DL-QVPEEILMPSIPPTPSPVTTPVPAVTPPALSPAPAVLHTGKGHIGLHDFNFLMVLGKGSFGK 376

  Fly   385 VLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVM 449
            |||||.:|::.|:|:|:|:|||:.|.:|.|..|.|:::|||||||.||.|::..|||.|||::||
Zfish   377 VLLAEEKGSERLFAIKMLKKDVLFQDEDTESAMVERRVLALSGRPHFLTSLYCAFQTEDRLYYVM 441

  Fly   450 EYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDF 514
            ||..|||||:|:|..|:|||..|.|||.|:|:.|||||.:.||||||||||:|||.|||:|:.||
Zfish   442 EYVNGGDLMFHIQIVGKFKEPHAAFYAAEIAVGLFFLHNKGIIYRDLKLDNVLLDSEGHIKIADF 506

  Fly   515 GLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVF 579
            |:.:||:.|..|||||||||:|:|||||:|.||..|.||||:||||:|.:|||.||:|.||..:|
Zfish   507 GMCREGMMEGDTTRTFCGTPDYIAPEIVAYQPYGKAVDWWSYGVLLYEMLAGQPPFDGIDEEELF 571

  Fly   580 RNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEP 644
            ::|.::...:||..|.||:.|....|||.|..|||.|..|.:|:..|||||.:|||:.|..|::|
Zfish   572 QSIMEQSVSYPKSLSREAVAICKGLLTKNPAKRLGGGEDAERELREHPFFRWIDWDRLERLEIQP 636

  Fly   645 PIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEF 696
            |.||....:|. .|||..||...:.|||:|...:..::|.:|..|:|||.||
Zfish   637 PFKPRSGGKKG-ENFDKFFTSTSSALTPSDPDVLAAINQEEFQDFTFMNSEF 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaC	NP_476863.1	C1_cPKC_nPKC_rpt1	71..123	CDD:410342	31/51 (61%)
		C1	137..190	CDD:412127	27/52 (52%)
		C2_PKC_alpha_gamma	194..324	CDD:175992	66/129 (51%)
		STKc_PKC	375..692	CDD:270722	172/316 (54%)
prkcg	XP_001921715.1	C1_cPKC_rpt1	54..108	CDD:410383	32/53 (60%)
		C1_cPKC_rpt2	121..174	CDD:410386	27/52 (52%)
		C2_PKC_alpha_gamma	178..308	CDD:175992	66/129 (51%)
		STKc_cPKC	366..684	CDD:270739	173/318 (54%)