DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6472 and PNLIP

DIOPT Version :9

Sequence 1:	NP_611166.2	Gene:	CG6472 / 36895	FlyBaseID:	FBgn0034166	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_000927.1	Gene:	PNLIP / 5406	HGNCID:	9155	Length:	465	Species:	Homo sapiens

Alignment Length:	356	Identity:	125/356 - (35%)
Similarity:	172/356 - (48%)	Gaps:	58/356 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LAGSPIFYSAAPRGSC----STCCAIKER---------EDI--KFMLYTSRNRNSAQLLHLSDDA 66
            :||..:.|.   |..|    |....|.||         :|:  :|:|||:.|.|:.|.: .:|.:
Human    14 VAGKEVCYE---RLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTNENPNNFQEV-AADSS 74

  Fly    67 RLAQSNFNFNYPLAIYLHGFSESATGERQSSQELKDAFLRRGNYNVILIDWSAMTAVPWYSNAVE 131
            .::.|||..|......:|||.:.  ||......:.....:..:.|.|.:||...:.. .|:.|.:
Human    75 SISGSNFKTNRKTRFIIHGFIDK--GEENWLANVCKNLFKVESVNCICVDWKGGSRT-GYTQASQ 136

  Fly   132 NLPVSGRYLARFLRFLVDK-GYPAKYIHLIGFSLGAEVAGFAGKQLQEWGIKLPRITALDPALPL 195
            |:.:.|..:|.|:.||... ||....:|:||.||||..||.||::...   .:.|||.||||.|.
Human   137 NIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNG---TIGRITGLDPAEPC 198

  Fly   196 FEGNSSNRRLSPSDARFVDVIHTDGGLL------GNPAPMGHADFYPNGGRPLQPGCAKQNIANN 254
            |:|.....||.||||:|||||||||..:      |....:||.||:||||..: ||| |:||.:.
Human   199 FQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGVEM-PGC-KKNILSQ 261

  Fly   255 -------WLGI--IVGCSHQRAWEYFVESIAQPRGFPAQRCEPSDMFGI-----CREPGGGPAFM 305
                   |.|.  ...|:|.|:::|:.:||..|.||....|...::|..     |  |.||...|
Human   262 IVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPC--PSGGCPQM 324

  Fly   306 GMGADPRIRG-------KFYLDTNDAKPFGR 329
            |..|| |..|       ||||||.||..|.|
Human   325 GHYAD-RYPGKTNDVGQKFYLDTGDASNFAR 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6472	NP_611166.2	Pancreat_lipase_like	43..323	CDD:238363	112/309 (36%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:278576	121/349 (35%)
PNLIP	NP_000927.1	PLAT_PL	355..465	CDD:238857	125/356 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940