DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6472 and Lipg

DIOPT Version :9

Sequence 1:	NP_611166.2	Gene:	CG6472 / 36895	FlyBaseID:	FBgn0034166	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus

Alignment Length:	340	Identity:	114/340 - (33%)
Similarity:	165/340 - (48%)	Gaps:	30/340 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NVFTFLLAGSPIFYSAAPRGSC------STCCAIKEREDIKFMLYTSRN-RNSAQLLHLSDDARL 68
            :|:.:..|||  ..:..|:||.      .|......|..:.|.:.||:: ......|.|.|...|
Mouse    12 SVYCYFPAGS--ITTLRPQGSLRDEHHKPTGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLL 74

  Fly    69 AQSNFNFNYPLAIYLHGFSESATGERQSSQELKDAFLRRGNYNVILIDWSAMTAVPWYSNAVENL 133
            ....||........:||::.|...|....:.:....:|..:.||:::||..: |...|::||.|.
Mouse    75 ENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQMREKDANVVVVDWLPL-AHQLYTDAVNNT 138

  Fly   134 PVSGRYLARFLRFLVDK-GYPAKYIHLIGFSLGAEVAGFAGKQLQEWGIKLPRITALDPALPLFE 197
            .|.|:.:|..|.:|.:| .:....:||||:||||.|||:||..::.   .:.|||.||||.|:||
Mouse   139 RVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAGYAGNFVKG---TVGRITGLDPAGPMFE 200

  Fly   198 GNSSNRRLSPSDARFVDVIHT---DGGL-LGNPAPMGHADFYPNGGRPLQPGCAKQNIANNW--- 255
            |...||||||.||.||||:||   ..|| :|...|:||.|.||||| ..||||...::..::
Mouse   201 GVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGG-DFQPGCGFNDVIGSFAYG 264

  Fly   256 -LGIIVGCSHQRAWEYFVESIA-QPRGFPAQRCEPSDMF--GIC----REPGGGPAFMGMGADPR 312
             :..:|.|.|:||...||:|:. |.:...|.:|..|..|  |||    :.......:.......:
Mouse   265 TISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKK 329

  Fly   313 IRGKFYLDTNDAKPF 327
            ...|.||.|....||
Mouse   330 RNSKMYLKTRAGMPF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6472	NP_611166.2	Pancreat_lipase_like	43..323	CDD:238363	103/296 (35%)
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	103/295 (35%)
		lipo_lipase	51..485	CDD:132274	105/299 (35%)
		Heparin-binding. /evidence=ECO:0000250	325..337		2/11 (18%)
		PLAT_LPL	347..483	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940