Protein Alignment Fen1 and RAD2

DIOPT Version :10

• Sequence 1: NP_523765.1
• Gene: Fen1 / 36887
• FlyBaseID: FBgn0025832
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_011774.1
• Gene: RAD2 / 853174
• SGDID: S000003490
• Length: 1031
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 89/353 - (25%)
• Similarity: 149/353 - (42%)
• Gaps: 79/353 - (22%)

  Fly    74 LLDNGIKPVYVFDGKPPDLKSGELAKRAERR---------EEAEKALKAATDAGDDAGIEKFNRR 129
            :::|.||....||    ..|:..|:..|||.         |..|:.:|...|:.:
Yeast   716 IVENMIKEQEEFD----TFKNTTLSTSAERNVAENAFVEDELFEQQMKDKRDSDE---------- 766

  Fly   130 LVRVTKEHAKEAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYL 194
               ||.:..||.:|||:..|:||:.||.|||||||.|::...|....|:|.|...||.||:.:.:
Yeast   767 ---VTMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNM 828

  Fly   195 TYSEARKMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCESIKGIGPKRAIELINTYRDIETI 259
            .:   .|..|:.:..:.:|:.|.::.:..|:|..|||.||...:||:||..:||:|..:.:::..
Yeast   829 FH---EKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGNLKNF 890

  Fly   260 LD-----NLDSSKYTVPENWNYKVAREL-------------------FIEPEVADADSIDLKWVE 300
            .|     ..|..|......:...:.::|                   ::.||| |.|:....|..
Yeast   891 KDWYNNGQFDKRKQETENKFEKDLRKKLVNNEIILDDDFPSVMVYDAYMRPEV-DHDTTPFVWGV 954

  Fly   301 PDEEGLVKFLCGDRQFNEER--------VRNGAKKLMKSKQAQTQVRLDSFFKTLPSTPNATNAA 357
            ||.:.|..|:.....:..|:        :|:..|:..|.||.    |::.||
Yeast   955 PDLDMLRSFMKTQLGWPHEKSDEILIPLIRDVNKRKKKGKQK----RINEFF------------- 1002

  Fly   358 KRKAEEAKKSANNKKAKTSGGGRGRRPK 385
            .|:.....|..|..|..::..|:.::.|
Yeast  1003 PREYISGDKKLNTSKRISTATGKLKKRK 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fen1	NP_523765.1	PTZ00217	1..363	CDD:240317	84/329 (26%)
RAD2	NP_011774.1	rad2	1..1030	CDD:273166	88/351 (25%)