DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fen1 and exo-1

DIOPT Version :10

Sequence 1:NP_523765.1 Gene:Fen1 / 36887 FlyBaseID:FBgn0025832 Length:385 Species:Drosophila melanogaster
Sequence 2:NP_499770.1 Gene:exo-1 / 176765 WormBaseID:WBGene00009731 Length:639 Species:Caenorhabditis elegans


Alignment Length:409 Identity:106/409 - (25%)
Similarity:165/409 - (40%) Gaps:76/409 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLM 65
            |||.||...:.:    |.|:..:....|:.||||.|..|::.|     .|.......|:.|...:
 Worm     1 MGISGLLPFVKN----ACRKGNILELRGKSVAIDVSCLLHRGL-----TGCMDKIHMGEETQSYV 56

  Fly    66 GMFYRTIR-LLDNGIKPVYVFDGKPPDLKSGELAKRAE----RREEAEKALKAATDAGDDAGIEK 125
            ....:.:: ||..|...|.||||:|...|.|...:|.|    |:|.||..|.        .|:|:
 Worm    57 NYVNKYVKELLGMGCHVVMVFDGRPLPAKKGTNEERRELREKRKEHAEMLLA--------KGLER 113

  Fly   126 FNRRLVRVTKEHAKEAKE-----LLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTF 185
            ..|...|:....:.:..|     ..::..|..|.||.||:||.|.||:...|.|..|||.|.:.|
 Worm   114 EARDTYRLATSISADIVENTIQYFRSMTNVDIVVAPYEADAQLAYLVQEKLVDAVITEDSDLIVF 178

  Fly   186 GSTKLLRYLTYSEARKMPVKEFS-YDKL---------LEGLAINNREFIDLCILLGCDYCES-IK 239
            |...:  |..:..|    ..|.| |:|.         |.|...:..:|..:|||.||||.:: :.
 Worm   179 GCEMI--YFKWQSA----TGECSVYEKCNLKNCFTGELGGDKFDFVKFRRICILSGCDYLQAGLP 237

  Fly   240 GIGPKRAIEL--INTYRDIETILDNLDS------SKYTVPENW--NYKVARELFIEPEVADADSI 294
            |:|...|.:.  :.:.:|:.|:|..:.|      .|..|.:.:  |::.|...|....|.|....
 Worm   238 GVGLSTAAKFFSMTSIKDLRTLLRKVPSYLKNPKLKEHVNDEFIRNFEKAENTFKHQIVFDPRER 302

  Fly   295 DLKWVEPDEEGLVKFLCGDRQFNEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPSTPNATNAAKR 359
            ..|.:.|              :.:|.:..|...|      :..:.|||..||.||:.:...|...
 Worm   303 CQKPLTP--------------YPKEVLMTGVDDL------EEVIDLDSPKKTAPSSKSFAYAGTA 347

  Fly   360 KAEE--AKKSANNKKAKTS 376
            ..:.  .:.:..|.:.|:|
 Worm   348 STQRIAIRLALGNPENKSS 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fen1NP_523765.1 PTZ00217 1..363 CDD:240317 103/392 (26%)
exo-1NP_499770.1 PIN_EXO1 1..204 CDD:350207 66/225 (29%)
H3TH_EXO1 219..298 CDD:188628 21/78 (27%)
PRK11198 <345..>400 CDD:236880 3/22 (14%)
PspC_subgroup_1 <497..>598 CDD:468201
Blue background indicates that the domain is not in the aligned region.

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