Protein Alignment Fen1 and gen-1

DIOPT Version :10

• Sequence 1: NP_523765.1
• Gene: Fen1 / 36887
• FlyBaseID: FBgn0025832
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_498361.1
• Gene: gen-1 / 175885
• WormBaseID: WBGene00020442
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 434
• Identity: 100/434 - (23%)
• Similarity: 159/434 - (36%)
• Gaps: 98/434 - (22%)

  Fly    10 IADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRL 74
            |.:.|...:|:...:....:.::||..:.||:.|....:...|      .|.|:|:..|.|..||
 Worm     6 IWEWANHVVRKVPNETMRDKTLSIDGHIWLYESLKGCEAHHQQ------TPNSYLVTFFTRIQRL 64

  Fly    75 LDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGDDAGIEKFNRRLVRVTKEHAK 139
            |:..|.|:.|||    ::.:...|.  |.:::.|...:.....||    ..|...:     :|..
 Worm    65 LELKIIPIVVFD----NINASSSAH--ESKDQNEFVPRKRRSFGD----SPFTNLV-----DHVY 114

  Fly   140 EAKELLTLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRY----LTYSEAR 200
            :...|||.:|:..:.||.:.|||||.|...|......|.|.|...||...|.|:    .|.|.|.
 Worm   115 KTNALLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITTDFDYFLFGGKNLYRFDFTAGTSSTAC 179

  Fly   201 KMPVKEFSYDKLLEGLAINNREFIDLCILLGCDYCE-SIKGIGPKRAIELI-------NTYRDIE 257
            ...:...|..::.....::....|...|||||||.: .::.||.....:::       |...|..
 Worm   180 LHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDYFQRGVQNIGIVSVFDILGEFGDDGNEEIDPH 244

  Fly   258 TILDNLDS-SKYTVP--------------ENWNYKV----------ARELFIEPEVADADSIDLK 297
            .|||...| .:..:|              :.:|:.|          |..:::.|.|    |.::.
 Worm   245 VILDRFASYVREEIPARSEDTQRKLRLRRKKYNFPVGFPNCDAVHNAITMYLRPPV----SSEIP 305

  Fly   298 WVEPDEEGLVKFL------CG---DRQFNEERVRNGAKKLMKSKQAQTQVRLDSFFKTLPS---T 350
            .:.|......:..      ||   .|...|..:....|..:.:..|||  |:..||....|   |
 Worm   306 KIIPRAANFQQVAEIMMKECGWPATRTQKELALSIRRKVHLTTTVAQT--RIPDFFAATKSKNFT 368

  Fly   351 P--------------NATNAAKRKAEE--------AKKSANNKK 372
            |              |.|...|||..|        ||:...::|
 Worm   369 PIVEPCESLEDYISANNTWMRKRKRSESPQILQHHAKRQVPDRK 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fen1	NP_523765.1	PTZ00217	1..363	CDD:240317	96/415 (23%)
gen-1	NP_498361.1	PIN_SF	3..>167	CDD:475124	48/181 (27%)
		rad2	<119..359	CDD:273166	57/245 (23%)