Protein Alignment IntS8 and ints8

DIOPT Version :9

• Sequence 1: NP_611162.2
• Gene: IntS8 / 36886
• FlyBaseID: FBgn0025830
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001018592.2
• Gene: ints8 / 553794
• ZFINID: ZDB-GENE-050522-556
• Length: 996
• Species: Danio rerio
• Alignment Length: 1085
• Identity: 289/1085 - (26%)
• Similarity: 464/1085 - (42%)
• Gaps: 195/1085 - (17%)

  Fly    11 PLAAETVLWFEFLLDPHKITQHLQRPHPEPSAMELIVQFISMTPNTAQESVGTPGSDLQNLNQTP 75
            |.......||||||:|..:.|||..|||:||.::||.||:        |....|..:.||..|.|
Zfish    16 PCTPPQTSWFEFLLNPSLLEQHLHSPHPDPSPVQLIFQFL--------EQASKPSVNEQNQVQPP 72

  Fly    76 SNSGPIPGVVGGAPAPTTPTASGGVGMPHSPQRPAEKGLQLNRKQLALKILELKVATWLKWDLDA 140
            .:                                       ||:...||::.||||..|:|||:.
Zfish    73 VD---------------------------------------NRRNRTLKLMALKVAAHLRWDLNM 98

  Fly   141 LEKNLPVIMQLALLRDLCTISYGCSLSIPLPNDFDARISAAGNERAARFALTIYHRMLLRMQLIK 205
            |||.|.:.:...||.:|..:|:     :| |......:..:........|:..|:|..:|..::.
Zfish    99 LEKGLTIPVLNMLLNELLCVSH-----VP-PGVKHVDLDLSSLPPTTAMAVVFYNRWAIRTIVLS 157

  Fly   206 EQALKAPRPQNTMYQTVDQLQQ----------FLDTPTQPSIEYLQQLCASTKPFYIFHYDSFVP 260
            ....|..:|.......::.|||          .|......||..|:...:..|.|||....:...
Zfish   158 SFPEKQTKPGPHQLNMMNMLQQEKEHTENILSVLREQATDSIVVLEGALSIKKDFYIHTLRTLDL 222

  Fly   261 LRCD-DIGNGQ-NYDVMHL-ITPQELRAQLHYELAQYYLY-----TKQYVLAREAAAACNTNLQA 317
            |..| ...||: .|....| |:...|..|:||:|...|..     |..|..|||........|..
Zfish   223 LAADPSTTNGETEYSTAGLRISFDHLHCQVHYDLGGIYFQQGCSDTSVYEKAREHFRKARELLTK 287

  Fly   318 IPPQTTLYYCHIRPSELEGLLQAC----GISAEEQSLLEKFQQSLL----NNYTDIVSILRMDNR 374
            :  ..:..:|.:....|.|...||    |.|...:|....:.|...    :||..::.....||.
Zfish   288 L--DFSASFCCLDEQRLAGYWSACRTLTGTSDLNESQHTPYGQISCFMRNHNYGALIEEFICDNV 350

  Fly   375 RREIPFISRRQVELDIEGSISTG--ILKETVQLQLQVAALNVVRNIFEWGSIFGSVEYFEKYREL 437
            ...:|...|..::|::...:..|  .|:|...   ::...|.||:..|.|.:  ||.:.:.
Zfish   351 TLSLPNSFRHSIQLELMHKLQQGDSALEEVCN---KLCVCNAVRDALEGGIL--SVSFHQL---- 406

  Fly   438 DCLPPLVEALQEMLPHCT-----------FKEQAALKHFLIDCLLHQGG--------QSRQLLQT 483
             .|.|....:..:|..||           .|.:.||   .|..:..|.|        .|.:|.:.
Zfish   407 -LLKPSKNIISFLLEVCTRSLEKENLPELSKSKMAL---FIKTVCDQLGDVSLAFMVSSHKLFKE 467

  Fly   484 VRGFGLFSSDELQDIDEQMLQATPPVPTNS--LASLSDWMCHSKMSRVDVGALERQLISCTNANT 546
                 |...:|.:.:.|||.:::..:..:|  |.|..|....:.   |::..||:|||...:|..
Zfish   468 -----LLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASAS---VNISQLEQQLILSLDARH 524

  Fly   547 VRILLVKLCATAPGKPLWAINPSWDVPQPLKTLIMAMPVSFLQDFSYVLLGKARELATRGNYIDA 611
            :|.:|::|...|. :|.|.:|..|:||.....:|:|:.....:|..|:||.|........:::.|
Zfish   525 IRQILIELHGMAE-RPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHA 588

  Fly   612 VSMLSVLK------SENQRQEMAANVQLMCKLITWEILHIQITQCLEEWHQK------PLDLQSL 664
            ..:.:...      |...||.|...:.||      |:      :..||...|      |.||.|
Zfish   589 CQLFTACLELVTEFSPKLRQVMLNELLLM------EV------RAHEEGTAKGRIVRPPPDLVS- 640

  Fly   665 GGRCKQCLGALQAGDSIVP-RPDILESCAIMLLNLTEFPPLLYLDKRAGPLELPLA--------- 719
                 :..|.|:.....:| |..:.|.|.:.:||..|..   ||     .|::|.:
Zfish   641 -----RVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENE---YL-----TLQVPQSLVNNNPYIK 692

  Fly   720 ----FAATFIEMEKMKGPKKVCRDAWELMLSM--FLNVPKR-------------GSSGVGGISSL 765
                .|:|..|:...|..::..::.||:::.:  |.:..||             .|.|:...|..
Zfish   693 LGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKF 757

  Fly   766 QAFLQRIRHQSVFGLAISMIGKVHNILKDDPNHDLSCEYMQLWPTSINNPVSYSLRSVCETLQWL 830
            ..|:::||...|....||:..::|:|::||..::::.|::.:||:|:.|..|..:.:|..||:.|
Zfish   758 ITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKEL 822

  Fly   831 LSEALSYYPQTISWLKMKGDLDLAIGNNESAMRCYVNALVTGTDYCTMPLQRNVADDYVIRKMIR 895
            ::.|||..|...|||..:.|:........:||..|:.|....:|:.|.|:..:|..|.|:::||:
Zfish   823 VNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIK 887

  Fly   896 CAANLGCHMQATVLCQFLDEIDYGIVFKNLSEKSSNFTDAMDAYYSCIWDTTLLEFIVNLHAKRG 960
            |.:.|.||.|..||||||.|:||...||.|.|::|:  |:||::|..|||.|:||::..:|.|||
Zfish   888 CCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSH--DSMDSFYDYIWDVTILEYLTYIHHKRG 950

  Fly   961 EHSRKLEAISMMGTLELNANNNEEIKRESAMVRKSRFLRALAKQY 1005
            |..::..||..:|..|||::|.||:.:.:|..||.|||:|:||.|
Zfish   951 ESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLY 995

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595676
Domainoid	1	1.000	297	1.000	Domainoid score	I1425
eggNOG	1	0.900	-	-		E1_2CA0B
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9888
Inparanoid	1	1.050	298	1.000	Inparanoid score	I2700
OMA	1	1.010	-	-		QHG46381
OrthoDB	1	1.010	-	-		D277934at33208
OrthoFinder	1	1.000	-	-		FOG0008167
OrthoInspector	1	1.000	-	-		oto40410
orthoMCL	1	0.900	-	-		OOG6_106555
Panther	1	1.100	-	-	LDO	PTHR13350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3335
SonicParanoid	1	1.000	-	-		X6130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800