Protein Alignment IntS8 and Ints8

DIOPT Version :10

• Sequence 1: NP_611162.2
• Gene: IntS8 / 36886
• FlyBaseID: FBgn0289323
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001414770.1
• Gene: Ints8 / 297823
• RGDID: 1310592
• Length: 995
• Species: Rattus norvegicus
• Alignment Length: 1082
• Identity: 283/1082 - (26%)
• Similarity: 477/1082 - (44%)
• Gaps: 190/1082 - (17%)

  Fly    11 PLAAETVLWFEFLLDPHKITQHLQRPHPEPSAMELIVQFISMTPNTAQESVGTPGSDLQNLNQTP 75
            |.......||||||:...:.:||::..|:|:.::|||||:        |....|..:.||..|.|
  Rat    16 PCTPPQTCWFEFLLEESLLEKHLRKACPDPAPVQLIVQFL--------EQASKPSVNEQNQVQPP 72

  Fly    76 SNSGPIPGVVGGAPAPTTPTASGGVGMPHSPQRPAEKGLQLNRKQLALKILELKVATWLKWDLDA 140
            .:                                       |::..:||:|.||||..||||||.
  Rat    73 PD---------------------------------------NKRNRSLKLLALKVAAHLKWDLDI 98

  Fly   141 LEKNLPVIMQLALLRDLCTISYGCSLSIPLPNDFDARISAAGNERAARFALTIYHRMLLRMQLIK 205
            |||:|.|.:...||.:|..:|     .:| |......:..|........|:.:|:|..:|..:..
  Rat    99 LEKSLSVPVLNMLLNELLCVS-----KVP-PGTKHVDVDLAALPPTTAMAILLYNRWAIRTIVQS 157

  Fly   206 EQALKAPRPQNTMYQTVDQLQQ----------FLDTPTQPSIEYLQQLCASTKPFYIFHYDSFVP 260
            ...:|..:|.......::|:||          .|......||..|:......|..|:.      .
  Rat   158 SFPVKQAKPGPPQLNVMNQMQQEKELTENILKVLREQAADSILVLEAALKLNKDLYVH------T 216

  Fly   261 LRCDDI---------GNGQNYDVMHLITPQELRAQLHYELAQYYLY-----TKQYVLAREAAAAC 311
            :|..|:         |..:|......|..:|::.|:.|:|...|..     :..|..|||.....
  Rat   217 MRTLDLLAVEPGTVNGETENSTAGLKIRTEEMQCQVCYDLGAAYFQQGSTNSAAYESAREKFFRT 281

  Fly   312 NTNLQAIPPQTTLYYCHIRPSELEGLLQACGI-----SAEEQSLLEKFQQSLL---NNYTDIVSI 368
            ...:..|  .:...:|.|....|.|..|||.:     ....|.:....|..:.   .:|.::|.|
  Rat   282 KELIAEI--GSLSLHCTIDEKRLAGYCQACDVLVPSSDTNSQQVTPYSQVHICLRSGSYQEVVQI 344

  Fly   369 LRMDNRRREIPFISRRQVELDIEGSISTGILKETV-QLQLQVAALNVVRNIFEWGSIFGSVEYFE 432
            ...||....:|...|:.|..::......|  .|.: ::..::.:.|.||:|.|..:|  ||::.:
  Rat   345 FIEDNVTFTLPVQFRQSVLRELFQKAQQG--NEALDEICFKICSCNTVRDILEGRTI--SVQFNQ 405

  Fly   433 KYRELDCLPPLVEALQEMLPHCTFK---EQAA------LKHFLID-CLLHQGGQSRQLLQTVRGF 487
            .:     |.|..|.:..:|..|:..   |:|:      :..||.: ||   |.:..|.:..:...
  Rat   406 LF-----LRPNKEKIDFLLEVCSRSIDIEKASDSLKGNMAAFLKNVCL---GLEDLQYVFMISSH 462

  Fly   488 GLF----SSDELQDIDEQMLQATPPV-----PTNSL----ASLSDWMCHSKMSRVDVGALERQLI 539
            .||    ..:|.:.:.:||.:.:|.|     |..|.    ||.|          |::|.||.|||
  Rat   463 ELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASAS----------VNIGQLEHQLI 517

  Fly   540 SCTNANTVRILLVKLCATAPGKPLWAINPSWDVPQPLKTLIMAMPVSFLQDFSYVLLGKARELAT 604
            ...:...:|.:|::|......:..|.::..|:||....|:|:.:..:..:|..|:|:.|....:|
  Rat   518 LSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSTVILGIKDNLTRDLVYILMAKGLHCST 582

  Fly   605 RGNYIDAVSMLS-----VLKSENQRQEMAANVQLMCKLITWE--ILHIQITQCLEEWHQKPLDLQ 662
            ..::..:..:.:     |.:...:.:::..|..|:..::|.|  :.|        ...:.|.||.
  Rat   583 VKDFPHSKQLFTAGLELVTEFSPKLRQVMLNEILLLDILTHEAGVGH--------SGERPPSDLI 639

  Fly   663 SLGGRCKQCLGALQAGDSIVP-RPDILESCAIMLLNLTE-------FPPLLYLDKRAGP-LELPL 718
            |      :..|.|:.....:| |..:...|...:||..|       .|..|:   :..| ::|..
  Rat   640 S------RVRGYLEMRLPDIPLRQVVAAECVAFMLNWRENEYLTLQVPAFLF---QNNPYVKLGQ 695

  Fly   719 AFAATFIEMEKMKGPKKVCRDAWELMLSM--FLNVPKRGSSG----------VGGI---SSLQAF 768
            ..|||..|:...|..::..:|.||:::.:  ..|..|||:.|          ..||   |.|.:|
  Rat   696 LLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKQRESTLGIMYRSELLSF 760

  Fly   769 LQRIRHQSVFGLAISMIGKVHNILKDDPNHDLSCEYMQLWPTSINNPVSYSLRSVCETLQWLLSE 833
            ::::|...|..:.:|:..|:||:.:|..| |::.|::.:||:||.|..|....:|..|::.::..
  Rat   761 IKKLREPLVLTIILSLFVKLHNVREDIVN-DITAEHISIWPSSIPNLQSVDFEAVAITVREVVRY 824

  Fly   834 ALSYYPQTISWLKMKGDLDLAIGNNESAMRCYVNALVTGTDYCTMPLQRNVADDYVIRKMIRCAA 898
            |||..|.:.:||.::.|:..|...:.:|:..|:.|....:|:....:..:|..|.||::||:|.:
  Rat   825 ALSVNPNSHAWLIIQADIYFATNQHSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCS 889

  Fly   899 NLGCHMQATVLCQFLDEIDYGIVFKNLSEKSSNFTDAMDAYYSCIWDTTLLEFIVNLHAKRGEHS 963
            .|.||.|..:|||||.||||...||:|.|::|:  ||||:||..|||.|:||::..||.||||..
  Rat   890 LLNCHTQVAILCQFLREIDYKTAFKSLQEQNSH--DAMDSYYDYIWDVTILEYLTYLHHKRGETD 952

  Fly   964 RKLEAISMMGTLELNANNNEEIKRESAMVRKSRFLRALAKQY 1005
            ::..||..:|..||||:|.||:.:.:|..||.:||:|:||.|
  Rat   953 KRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLY 994