Protein Alignment IntS8 and ints-8

DIOPT Version :9

• Sequence 1: NP_611162.2
• Gene: IntS8 / 36886
• FlyBaseID: FBgn0025830
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_001252168.1
• Gene: ints-8 / 173216
• WormBaseID: WBGene00013021
• Length: 977
• Species: Caenorhabditis elegans
• Alignment Length: 1184
• Identity: 225/1184 - (19%)
• Similarity: 375/1184 - (31%)
• Gaps: 404/1184 - (34%)

  Fly    11 PLAAETVLWFEFLLDPHKITQHLQRPHPEPSAMELIVQFISMTPNTAQESVGTPGSDLQNLNQTP 75
            |.:...|.|||..:||..|::.|..|........|.:||                :|...|.:..
 Worm     4 PESTGDVSWFELFVDPTCISKSLLDPEKRKQLPRLCMQF----------------TDKGFLAERE 52

  Fly    76 SNSGPIPGVVGGAPAPTTPTASGGVGMPHSPQRPAEKGLQLNRKQLALKILELKVATWLKWDLDA 140
            .:.|.:                           ..|:.:...||..::::..:.....|.:|::.
 Worm    53 KDKGKL---------------------------AVEELMLFERKAASMRLCAMATFAALDYDIEF 90

  Fly   141 LEKNLP--VIMQLALLRDLCTISYGCSLSIPLPNDFDARISAAGNERAARFALTIYHRMLLRMQL 203
            :..|:|  .|..|.:|.|.....|.       ..:.||..   ||....||.|:|..|
 Worm    91 IIDNIPRNEIQTLRVLADNFYRIYN-------EKNLDATF---GNWLFYRFVLSIDRR------- 138

  Fly   204 IKEQALKAPRPQNTMYQTVDQLQQFLDTPTQPSI---EYLQQLCASTKPFYIFHYDSFVP----- 260
               ..|..|.|:.|:..|:...|..   ||.|::   |..|:.....|. ::....:|:.
 Worm   139 ---NRLAPPAPRATIPTTLSNGQLM---PTDPALLKHEKTQRTIMELKE-HVLKARAFITELAEV 196

  Fly   261 --------LRC----------------------------------DDI----GNGQNYDVMHLIT 279
                    ::|                                  |.:    |:..|..:..|:|
 Worm   197 PRDVVAPGIQCFLKPFVELAPKAMTAAFLGDRNVLIENPSADFEVDKVLLSAGDVSNKCLSELVT 261

  Fly   280 PQELRAQLHYELAQYYLYTK------QYVLAREAAAACNTNLQAIPPQTTLYYCHIRPSELEGLL 338
                           :|:|.      :.:|.|.........|.||.......||.|        |
 Worm   262 ---------------FLFTSGELQEAKKILTRVVKPTVTHPLVAIDETIFKSYCQI--------L 303

  Fly   339 QACGISAEEQSLLEKFQQSLLNNYT-DIVSILRMDNRRREIPFISRRQVELDIEGSISTGILKET 402
            .|.|......:.    ..|||..|. |:.|:.....||.|:  :..|            |:.:.|
 Worm   304 NAQGTPYSSSTA----SSSLLKPYVFDLNSLNDEKMRRSEV--LRHR------------GVQETT 350

  Fly   403 VQLQLQVAALNVVRNIFEWGSIFGSVEYFEKYRELDCLPPLVEALQEMLPHCTFKEQAALKHFLI 467
            .|||....|.|...::.:        |:.|..||                  :.:.:|.::.| :
 Worm   351 GQLQNVYLAENAALSVID--------EHPECIRE------------------SIRNRAEIERF-V 388

  Fly   468 DCLLHQ--GGQSRQLLQTVRG---FGLFSSDELQDIDE----------------QMLQATPPVPT 511
            ..|..:  |.:.::.|..:|.   :...|..:|:||.|                :.|:..||...
 Worm   389 KVLKRKTDGIRDKRKLAAIRAHLQYLCASISDLRDILETNGMDVSQLRTFAVPSEHLKLEPPPAF 453

  Fly   512 NSLASLSDWMCHSKMSRVDVGALERQLISCTNANTVRILLVKLCATAPGKPLWAINPSWDVPQ-- 574
            :.|..|...              ||::.:....:|..|..:.....| ..|.|.|...:|:|.
 Worm   454 HVLEELVSG--------------ERKIDAAQGPSTHEISRIFPLPRA-ADPYWIIMTEYDIPTLQ 503

  Fly   575 -----------PLKTLIMAMPVSFLQ-----------DFSYVLLGKARELATRGNYIDAVSMLSV 617
                       |.|   |.:|...::           :...:||.|..:|:...::.....:||:
 Worm   504 NALTKLGPFWFPTK---MQVPEHLMEKLEKHSNLPTYNLHRLLLCKIDQLSKMHHFEKFKDVLSL 565

  Fly   618 ----LKSENQRQEMAANVQ-------LMCKLITWEILHIQ----ITQCL-EEWHQKPLDLQSLGG 666
                ||..::...|.|..:       ::.:...||...::    .||.: ...|..|.|..:  |
 Worm   566 ALHSLKLVHESWVMTAAFEMIQVPAIIVNQQFAWERHSLERDFAQTQLIFNSDHFVPNDYSA--G 628

  Fly   667 RCKQCLGALQAGDSIVPRPDILESCAIMLLNLTEFPPLLYLDKRAGPLEL------PLA--FAAT 723
            ...:|||                    :::|:.:...:|   ::.|.|.:      |:|  |.|.
 Worm   629 MINECLG--------------------LMINIGDAQSVL---EKGGQLSMERFKSVPIARMFGAY 670

  Fly   724 FIEMEKMKGPKKVCRDAWELMLSMFLNV-PKRGSSGVGGISSLQAFL-------------QRIRH 774
            .:........||.....|..:....|.. |.||..  .|....||.|             ..||.
 Worm   671 LVNYSDPATRKKCADGFWRTVTQRLLEAQPPRGFR--RGNEVEQALLVTRKELADLFHLFSLIRD 733

  Fly   775 QSV--FGLAIS-------MIG------KVHNILKD----DPNHDLSCEYMQLWPTSINNPVSYSL 820
            |.|  |.||.:       :||      |:|..|.|    |||..         ...|:||
 Worm   734 QRVVDFLLAYAVCLHNKVVIGQRKSNLKIHAKLLDLYTPDPNAP---------KIDISNP----- 784

  Fly   821 RSVCETLQWLLSEALSYYPQTISWLKMKGDLDLAIGNNESAMRCYVNALVTGTDYCT--MPLQR- 882
            ..|.:.||.::.:|.|..|.....::...|......:.:.|.:.|:       :|.|  .|..|
 Worm   785 DDVRQLLQLMVEKAYSLSPTDPDTIRTYADFLYVERDFQGAAQKYM-------EYFTAHSPTLRL 842

  Fly   883 ------NVADDYVIRKMIRCAANLGCHMQATVLCQFLDEIDYGIVFKNLSEKSSNFTDAMDAYYS 941
                  .|.||.|::::..|.||.|....:.:.||:|.........|.::....|  :..|...:
 Worm   843 SPFDAFTVFDDTVVQRLRYCTANAGYLTMSLLTCQWLKVGKTNAYQKAMAVLEHN--ETRDVGAN 905

  Fly   942 C---IWDTTLLEFIVNLHAKRGEHSRKLEAISMMGTL-----ELNANNN-------EEIKRESAM 991
            |   :.|...:|.:       .:|...:.....:.||     .|:||.|       :||.|
 Worm   906 CADYVTDVVAIELL-------SQHYHSMMMTKSLDTLYTGANSLSANKNVPQVLATQEINR---- 959

  Fly   992 VRKSRFLRALAKQY 1005
             |.::||.||:..|
 Worm   960 -RTTKFLTALSSIY 972

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167086
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46381
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106555
Panther	1	1.100	-	-	LDO	PTHR13350
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3335
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970