DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5550 and Angpt2

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_604449.1	Gene:	Angpt2 / 89805	RGDID:	621861	Length:	496	Species:	Rattus norvegicus

Alignment Length:	246	Identity:	77/246 - (31%)
Similarity:	118/246 - (47%)	Gaps:	22/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LFYLASAEIGENVKIQTYKKYS-SSCKELNPKKSGVQKIQV-------GSDVIEVYCDVTIAGKG 71
            |..::|.:...:|.:...:|.: ..|.|:  .|||:....:       .::.::.|||:.:.|.|
  Rat   259 LTMMSSPDYKSSVAVPKEEKTTFRDCAEI--FKSGLTTSGIYTLTFPNSTEEVKAYCDMDMGGGG 321

  Fly    72 WLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAH 136
            |.|:|.|.....:|.|.|..|:.|||...|.:::|...:::::|.....|.|:|.|:.|.:.::.
  Rat   322 WTVIQHREDGSVDFQRTWKEYKEGFGSPLGEYWLGNEFVSQLTSGHRYVLKIQLKDWEGSEAHSL 386

  Fly   137 YSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQP---FSTFDRDNDNATINCAARYMGAWWYR 198
            |..|::....|||.| .|...:||||...|  :.||   |||.|.|||.....|:....|.||:.
  Rat   387 YEHFYLSGEESNYRI-HLTGLTGTAGKISS--ISQPGSDFSTKDSDNDKCICKCSQMLTGGWWFD 448

  Fly   199 ECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            .|    ..|||||.|..........  :||.|..|||..||.|...:|:||
  Rat   449 AC----GPSNLNGQYYPQKQNTNKF--NGIKWYYWKGSGYSLKATTMMIRP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	74/227 (33%)
Angpt2	NP_604449.1	Mplasa_alph_rch	<78..>232	CDD:275316
Angpt2	NP_604449.1	FBG	280..494	CDD:214548	73/225 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810