DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and FIBCD1

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001138578.1	Gene:	FIBCD1 / 84929	HGNCID:	25922	Length:	461	Species:	Homo sapiens

Alignment Length:	196	Identity:	85/196 - (43%)
Similarity:	114/196 - (58%)	Gaps:	15/196 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 EVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIE 124
            :||||:...|.||.|.|||.....||:|.|.:|:.|||.|.|..::||..::.:::....||:::
Human   270 QVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVD 334

  Fly   125 LVDFAGEKRYAHYSVFHVGNVYS------NYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNA 183
            |.||.....||.|..|.|| ::|      .||:| :..|||||||||..|....|:|.|||:|::
Human   335 LEDFENGTAYARYGSFGVG-LFSVDPEEDGYPLT-VADYSGTAGDSLLKHSGMRFTTKDRDSDHS 397

  Fly   184 TINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVR 248
            ..||||.|.||||||.|.:    |||||.||.|.|   |.:..|:.|..|.|:.||.|...:.:|
Human   398 ENNCAAFYRGAWWYRNCHT----SNLNGQYLRGAH---ASYADGVEWSSWTGWQYSLKFSEMKIR 455

  Fly   249 P 249
            |
Human   456 P 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	85/196 (43%)
FIBCD1	NP_001138578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..238
		FReD	241..457	CDD:238040	85/196 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3915
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm40314
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.960