DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and angptl2a

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001025401.1	Gene:	angptl2a / 569092	ZFINID:	ZDB-GENE-080721-15	Length:	525	Species:	Danio rerio

Alignment Length:	227	Identity:	78/227 - (34%)
Similarity:	126/227 - (55%)	Gaps:	20/227 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SSCKELNPKKSGVQKIQVG--------------SDVIEVYCDVTIAGKGWLVVQRRVSVEENFYR 87
            |:.|...|.|..:|.::.|              :.:::|:||......||.|:|||:....||:|
Zfish   299 STDKLSGPFKDCLQALEEGHSNSGMFLLKPENTNKLMQVWCDQRHDPGGWTVIQRRMDGSVNFFR 363

  Fly    88 NWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPIT 152
            ||.:|:.|||::.|.:::||.|:..:::....:|.:.|.|::|.|.:|.|:.|.:......|.:
Zfish   364 NWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEADFYKM- 427

  Fly   153 QLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGN 217
            ::|.|.|.||||:::|..:.|:|.|||:|..|.|||....|.|||..|..    |||||.:..|.
Zfish   428 RVGRYHGNAGDSMTWHNGKQFTTLDRDHDAYTGNCAHYQKGGWWYNACAH----SNLNGVWYRGG 488

  Fly   218 HTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            |. .:.:..|:.|.|::|.:||.|.|.:|:||
Zfish   489 HY-RSRYQDGVYWAEFRGGSYSLKKVTMMIRP 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	78/227 (34%)
angptl2a	NP_001025401.1	DUF1875	<50..>147	CDD:286100
		Fib_alpha	119..215	CDD:285864
		FReD	305..519	CDD:238040	74/219 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6515
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810